KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKIRAS2
All Species:
31.82
Human Site:
Y86
Identified Species:
50
UniProt:
Q9NYR9
Number Species:
14
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYR9
NP_001001349.1
191
21508
Y86
T
D
G
Y
V
L
V
Y
S
T
D
S
R
E
S
Chimpanzee
Pan troglodytes
XP_511498
329
36197
Y224
T
D
G
Y
V
L
V
Y
S
T
D
S
R
E
S
Rhesus Macaque
Macaca mulatta
XP_001093984
331
35945
Y226
T
D
G
Y
V
L
V
Y
S
T
D
S
R
E
S
Dog
Lupus familis
XP_534244
192
21653
Y86
A
D
G
F
V
L
V
Y
S
V
N
N
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR56
191
21476
Y86
T
D
G
Y
V
L
V
Y
S
T
D
S
R
E
S
Rat
Rattus norvegicus
P63033
266
30178
F98
G
D
V
F
I
L
V
F
S
L
D
S
R
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508842
191
21601
Y86
T
D
G
F
V
L
V
Y
S
T
D
S
R
E
S
Chicken
Gallus gallus
Q5ZJW6
191
21484
Y86
T
D
G
Y
V
L
V
Y
S
T
D
S
K
E
S
Frog
Xenopus laevis
Q32NS2
163
18379
E70
R
G
L
K
D
G
L
E
L
P
K
H
C
F
C
Zebra Danio
Brachydanio rerio
Q6DGL2
192
21894
Y86
A
D
G
F
V
L
V
Y
S
I
D
S
R
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4L4
201
22789
L91
Q
F
P
D
A
F
V
L
V
Y
D
P
M
D
P
Honey Bee
Apis mellifera
XP_395111
201
22615
D86
R
H
Y
L
G
F
A
D
G
Y
I
L
V
Y
D
Nematode Worm
Caenorhab. elegans
Q19143
199
22551
L86
Q
A
A
D
A
F
V
L
V
Y
S
S
A
D
Y
Sea Urchin
Strong. purpuratus
XP_001202670
179
20160
Y87
S
E
D
L
P
K
Q
Y
L
S
M
A
D
G
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P16976
208
23293
I90
G
I
I
I
V
Y
D
I
T
D
M
E
S
F
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.5
53.4
70.8
N.A.
98.9
24.4
N.A.
90.5
92.6
63.8
78.1
N.A.
38.3
47.2
42.2
49.2
Protein Similarity:
100
56.5
57
83.8
N.A.
100
37.2
N.A.
96.8
97.3
75.3
87.5
N.A.
56.2
64.6
55.7
64.9
P-Site Identity:
100
100
100
60
N.A.
100
60
N.A.
93.3
93.3
0
80
N.A.
13.3
0
13.3
6.6
P-Site Similarity:
100
100
100
80
N.A.
100
80
N.A.
100
100
6.6
86.6
N.A.
20
0
20
33.3
Percent
Protein Identity:
N.A.
25
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
44.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
0
14
0
7
0
0
0
0
7
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
7
% C
% Asp:
0
60
7
14
7
0
7
7
0
7
60
0
7
14
7
% D
% Glu:
0
7
0
0
0
0
0
7
0
0
0
7
0
60
0
% E
% Phe:
0
7
0
27
0
20
0
7
0
0
0
0
0
14
7
% F
% Gly:
14
7
54
0
7
7
0
0
7
0
0
0
0
7
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
7
0
0
0
% H
% Ile:
0
7
7
7
7
0
0
7
0
7
7
0
0
0
0
% I
% Lys:
0
0
0
7
0
7
0
0
0
0
7
0
7
0
0
% K
% Leu:
0
0
7
14
0
60
7
14
14
7
0
7
7
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
14
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
7
% N
% Pro:
0
0
7
0
7
0
0
0
0
7
0
7
0
0
7
% P
% Gln:
14
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
14
0
0
0
0
0
0
0
0
0
0
0
47
0
0
% R
% Ser:
7
0
0
0
0
0
0
0
60
7
7
60
7
0
60
% S
% Thr:
40
0
0
0
0
0
0
0
7
40
0
0
0
0
0
% T
% Val:
0
0
7
0
60
0
74
0
14
7
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
34
0
7
0
60
0
20
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _