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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKIRAS1 All Species: 32.73
Human Site: S169 Identified Species: 55.38
UniProt: Q9NYS0 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYS0 NP_065078.1 192 21643 S169 T L L A S K L S Q P Q S K S S
Chimpanzee Pan troglodytes XP_516327 192 21626 S169 T L L A S K L S Q P Q S K S S
Rhesus Macaque Macaca mulatta XP_001090211 192 21597 S169 T L L A S K L S Q P Q S K S S
Dog Lupus familis XP_534244 192 21653 S169 T L L A S K L S Q P Q S K S S
Cat Felis silvestris
Mouse Mus musculus Q8CEC5 192 21643 S169 T L L A S K L S Q P Q S K S S
Rat Rattus norvegicus Q5BJQ5 217 24743 R182 Q G L V R E I R R K E S M L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508842 191 21601 T169 V Y L V S K M T Q P Q S K S A
Chicken Gallus gallus Q5ZJW6 191 21484 T169 I Y L A S K M T Q P Q S K S A
Frog Xenopus laevis Q32NS2 163 18379 A141 A A Q Q W A K A E K I L L R N
Zebra Danio Brachydanio rerio Q6DGQ1 192 21527 T169 T S L T S R L T Q P Q S K S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4L4 201 22789 H178 T T L C A R L H P M Q T K S T
Honey Bee Apis mellifera XP_395111 201 22615 N178 V N L S S R L N P P T N K S T
Nematode Worm Caenorhab. elegans Q19143 199 22551 F171 H Y V G H R H F H P T K E S K
Sea Urchin Strong. purpuratus XP_001202670 179 20160 T153 V S L T S K L T I P P T K S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 99.4 98.4 N.A. 95.3 23.9 N.A. 67.1 70.3 54.1 72.9 N.A. 40.2 43.7 42.2 45.3
Protein Similarity: 100 98.9 100 100 N.A. 99.4 40.5 N.A. 84.3 83.3 68.7 89 N.A. 59.2 61.6 54.2 64
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 60 66.6 0 66.6 N.A. 40 40 13.3 46.6
P-Site Similarity: 100 100 100 100 N.A. 100 46.6 N.A. 80 86.6 20 86.6 N.A. 66.6 73.3 33.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 43 8 8 0 8 0 0 0 0 0 0 22 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 0 0 8 0 8 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 0 0 0 8 0 8 8 8 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 0 8 0 8 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 0 58 8 0 0 15 0 8 79 0 8 % K
% Leu: 0 36 86 0 0 0 65 0 0 0 0 8 8 8 0 % L
% Met: 0 0 0 0 0 0 15 0 0 8 0 0 8 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 0 0 0 8 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 15 79 8 0 0 0 0 % P
% Gln: 8 0 8 8 0 0 0 0 58 0 65 0 0 0 0 % Q
% Arg: 0 0 0 0 8 29 0 8 8 0 0 0 0 8 0 % R
% Ser: 0 15 0 8 72 0 0 36 0 0 0 65 0 86 43 % S
% Thr: 50 8 0 15 0 0 0 29 0 0 15 15 0 0 22 % T
% Val: 22 0 8 15 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 22 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _