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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKIRAS1
All Species:
40.91
Human Site:
S175
Identified Species:
69.23
UniProt:
Q9NYS0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYS0
NP_065078.1
192
21643
S175
L
S
Q
P
Q
S
K
S
S
F
P
L
P
G
R
Chimpanzee
Pan troglodytes
XP_516327
192
21626
S175
L
S
Q
P
Q
S
K
S
S
F
P
L
P
G
R
Rhesus Macaque
Macaca mulatta
XP_001090211
192
21597
S175
L
S
Q
P
Q
S
K
S
S
F
P
L
P
G
R
Dog
Lupus familis
XP_534244
192
21653
S175
L
S
Q
P
Q
S
K
S
S
F
P
L
P
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEC5
192
21643
S175
L
S
Q
P
Q
S
K
S
S
F
P
L
P
G
R
Rat
Rattus norvegicus
Q5BJQ5
217
24743
L188
I
R
R
K
E
S
M
L
S
L
V
E
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508842
191
21601
S175
M
T
Q
P
Q
S
K
S
A
F
P
L
S
R
K
Chicken
Gallus gallus
Q5ZJW6
191
21484
S175
M
T
Q
P
Q
S
K
S
A
F
P
L
S
R
K
Frog
Xenopus laevis
Q32NS2
163
18379
R147
K
A
E
K
I
L
L
R
N
G
P
T
H
G
S
Zebra Danio
Brachydanio rerio
Q6DGQ1
192
21527
S175
L
T
Q
P
Q
S
K
S
A
F
P
L
P
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4L4
201
22789
S184
L
H
P
M
Q
T
K
S
T
F
P
Q
L
R
Q
Honey Bee
Apis mellifera
XP_395111
201
22615
S184
L
N
P
P
T
N
K
S
T
F
P
Q
L
S
M
Nematode Worm
Caenorhab. elegans
Q19143
199
22551
S177
H
F
H
P
T
K
E
S
K
F
S
L
S
K
K
Sea Urchin
Strong. purpuratus
XP_001202670
179
20160
S159
L
T
I
P
P
T
K
S
T
F
S
I
S
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
99.4
98.4
N.A.
95.3
23.9
N.A.
67.1
70.3
54.1
72.9
N.A.
40.2
43.7
42.2
45.3
Protein Similarity:
100
98.9
100
100
N.A.
99.4
40.5
N.A.
84.3
83.3
68.7
89
N.A.
59.2
61.6
54.2
64
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
60
60
13.3
86.6
N.A.
40
40
26.6
40
P-Site Similarity:
100
100
100
100
N.A.
100
33.3
N.A.
86.6
86.6
33.3
100
N.A.
60
60
40
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
22
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
8
0
0
0
0
8
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
86
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
8
0
0
0
50
0
% G
% His:
8
8
8
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
0
15
0
8
79
0
8
0
0
0
0
15
22
% K
% Leu:
65
0
0
0
0
8
8
8
0
8
0
65
15
0
8
% L
% Met:
15
0
0
8
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
15
79
8
0
0
0
0
0
79
0
43
0
0
% P
% Gln:
0
0
58
0
65
0
0
0
0
0
0
15
0
0
8
% Q
% Arg:
0
8
8
0
0
0
0
8
0
0
0
0
8
22
50
% R
% Ser:
0
36
0
0
0
65
0
86
43
0
15
0
29
8
8
% S
% Thr:
0
29
0
0
15
15
0
0
22
0
0
8
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _