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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKIRAS1 All Species: 27.27
Human Site: S176 Identified Species: 46.15
UniProt: Q9NYS0 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYS0 NP_065078.1 192 21643 S176 S Q P Q S K S S F P L P G R K
Chimpanzee Pan troglodytes XP_516327 192 21626 S176 S Q P Q S K S S F P L P G R K
Rhesus Macaque Macaca mulatta XP_001090211 192 21597 S176 S Q P Q S K S S F P L P G R K
Dog Lupus familis XP_534244 192 21653 S176 S Q P Q S K S S F P L P G R K
Cat Felis silvestris
Mouse Mus musculus Q8CEC5 192 21643 S176 S Q P Q S K S S F P L P G R K
Rat Rattus norvegicus Q5BJQ5 217 24743 S189 R R K E S M L S L V E R K L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508842 191 21601 A176 T Q P Q S K S A F P L S R K N
Chicken Gallus gallus Q5ZJW6 191 21484 A176 T Q P Q S K S A F P L S R K N
Frog Xenopus laevis Q32NS2 163 18379 N148 A E K I L L R N G P T H G S A
Zebra Danio Brachydanio rerio Q6DGQ1 192 21527 A176 T Q P Q S K S A F P L P G R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4L4 201 22789 T185 H P M Q T K S T F P Q L R Q V
Honey Bee Apis mellifera XP_395111 201 22615 T185 N P P T N K S T F P Q L S M G
Nematode Worm Caenorhab. elegans Q19143 199 22551 K178 F H P T K E S K F S L S K K L
Sea Urchin Strong. purpuratus XP_001202670 179 20160 T160 T I P P T K S T F S I S V R N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 99.4 98.4 N.A. 95.3 23.9 N.A. 67.1 70.3 54.1 72.9 N.A. 40.2 43.7 42.2 45.3
Protein Similarity: 100 98.9 100 100 N.A. 99.4 40.5 N.A. 84.3 83.3 68.7 89 N.A. 59.2 61.6 54.2 64
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 60 60 13.3 86.6 N.A. 33.3 33.3 26.6 33.3
P-Site Similarity: 100 100 100 100 N.A. 100 33.3 N.A. 80 80 33.3 100 N.A. 53.3 53.3 40 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 0 0 0 0 0 22 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 8 0 8 0 0 0 0 8 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 86 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 8 0 0 0 50 0 8 % G
% His: 8 8 0 0 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 15 0 8 79 0 8 0 0 0 0 15 22 50 % K
% Leu: 0 0 0 0 8 8 8 0 8 0 65 15 0 8 8 % L
% Met: 0 0 8 0 0 8 0 0 0 0 0 0 0 8 0 % M
% Asn: 8 0 0 0 8 0 0 8 0 0 0 0 0 0 22 % N
% Pro: 0 15 79 8 0 0 0 0 0 79 0 43 0 0 0 % P
% Gln: 0 58 0 65 0 0 0 0 0 0 15 0 0 8 0 % Q
% Arg: 8 8 0 0 0 0 8 0 0 0 0 8 22 50 0 % R
% Ser: 36 0 0 0 65 0 86 43 0 15 0 29 8 8 0 % S
% Thr: 29 0 0 15 15 0 0 22 0 0 8 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _