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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NKIRAS1 All Species: 39.09
Human Site: Y43 Identified Species: 66.15
UniProt: Q9NYS0 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYS0 NP_065078.1 192 21643 Y43 C E T M E D V Y M A S V E T D
Chimpanzee Pan troglodytes XP_516327 192 21626 Y43 C E T M E D V Y M A S V E T D
Rhesus Macaque Macaca mulatta XP_001090211 192 21597 Y43 C E T M E D V Y M A S V E T D
Dog Lupus familis XP_534244 192 21653 Y43 C E T M E D V Y M A S V E T D
Cat Felis silvestris
Mouse Mus musculus Q8CEC5 192 21643 Y43 C E T L E D V Y M A S V E T D
Rat Rattus norvegicus Q5BJQ5 217 24743 A56 H D P T I E D A Y K T Q V R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508842 191 21601 Y43 M E T Q E D I Y V G S I E T E
Chicken Gallus gallus Q5ZJW6 191 21484 Y43 I E T Q E D I Y V G S I E T D
Frog Xenopus laevis Q32NS2 163 18379 G32 L Y G N H V V G S D M I E T Q
Zebra Danio Brachydanio rerio Q6DGQ1 192 21527 Y43 S D T Q E D I Y V A S V E T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4L4 201 22789 Y48 H P T I E D I Y V A S V D T G
Honey Bee Apis mellifera XP_395111 201 22615 Y43 H P T I E D I Y V A N I E T D
Nematode Worm Caenorhab. elegans Q19143 199 22551 Y43 E P T I E D T Y Q V L L E E P
Sea Urchin Strong. purpuratus XP_001202670 179 20160 H40 E Q V I Y G T H R V G Q E T T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 99.4 98.4 N.A. 95.3 23.9 N.A. 67.1 70.3 54.1 72.9 N.A. 40.2 43.7 42.2 45.3
Protein Similarity: 100 98.9 100 100 N.A. 99.4 40.5 N.A. 84.3 83.3 68.7 89 N.A. 59.2 61.6 54.2 64
P-Site Identity: 100 100 100 100 N.A. 93.3 0 N.A. 53.3 60 20 66.6 N.A. 53.3 53.3 33.3 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 80 80 26.6 86.6 N.A. 80 86.6 46.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 58 0 0 0 0 0 % A
% Cys: 36 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 0 79 8 0 0 8 0 0 8 0 58 % D
% Glu: 15 50 0 0 79 8 0 0 0 0 0 0 86 8 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 8 0 8 0 15 8 0 0 0 8 % G
% His: 22 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 29 8 0 36 0 0 0 0 29 0 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % K
% Leu: 8 0 0 8 0 0 0 0 0 0 8 8 0 0 0 % L
% Met: 8 0 0 29 0 0 0 0 36 0 8 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 22 8 0 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 8 0 22 0 0 0 0 8 0 0 15 0 0 8 % Q
% Arg: 0 0 0 0 0 0 0 0 8 0 0 0 0 8 0 % R
% Ser: 8 0 0 0 0 0 0 0 8 0 65 0 0 0 0 % S
% Thr: 0 0 79 8 0 0 15 0 0 0 8 0 0 86 8 % T
% Val: 0 0 8 0 0 8 43 0 36 15 0 50 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 8 0 0 79 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _