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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NKIRAS1
All Species:
21.21
Human Site:
Y75
Identified Species:
35.9
UniProt:
Q9NYS0
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYS0
NP_065078.1
192
21643
Y75
G
V
E
L
P
K
H
Y
F
S
F
A
D
G
F
Chimpanzee
Pan troglodytes
XP_516327
192
21626
Y75
G
V
E
L
P
K
H
Y
F
S
F
A
D
G
F
Rhesus Macaque
Macaca mulatta
XP_001090211
192
21597
Y75
G
V
E
L
P
K
H
Y
F
S
F
A
D
G
F
Dog
Lupus familis
XP_534244
192
21653
Y75
G
V
E
L
P
K
H
Y
F
S
F
A
D
G
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CEC5
192
21643
Y75
G
V
E
L
P
K
H
Y
F
S
F
A
D
G
F
Rat
Rattus norvegicus
Q5BJQ5
217
24743
Y88
F
T
A
M
R
E
Q
Y
M
R
G
G
E
G
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508842
191
21601
C75
G
T
D
L
P
R
H
C
F
S
C
T
D
G
F
Chicken
Gallus gallus
Q5ZJW6
191
21484
C75
G
L
E
L
P
K
H
C
F
S
C
T
D
G
Y
Frog
Xenopus laevis
Q32NS2
163
18379
G64
V
R
F
Y
D
T
R
G
L
K
D
G
L
E
L
Zebra Danio
Brachydanio rerio
Q6DGQ1
192
21527
F75
G
L
D
L
P
K
H
F
F
S
V
A
D
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V4L4
201
22789
R80
G
E
Q
Q
Q
L
P
R
H
Y
L
Q
F
P
D
Honey Bee
Apis mellifera
XP_395111
201
22615
Q75
L
Q
N
N
S
N
N
Q
Q
L
P
R
H
Y
L
Nematode Worm
Caenorhab. elegans
Q19143
199
22551
K75
Y
G
P
I
E
L
K
K
A
Y
V
Q
A
A
D
Sea Urchin
Strong. purpuratus
XP_001202670
179
20160
Y72
S
R
E
R
V
R
F
Y
D
T
K
G
L
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
99.4
98.4
N.A.
95.3
23.9
N.A.
67.1
70.3
54.1
72.9
N.A.
40.2
43.7
42.2
45.3
Protein Similarity:
100
98.9
100
100
N.A.
99.4
40.5
N.A.
84.3
83.3
68.7
89
N.A.
59.2
61.6
54.2
64
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
60
66.6
0
73.3
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
73.3
80
0
93.3
N.A.
13.3
6.6
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
8
0
0
43
8
8
0
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
15
0
0
0
0
% C
% Asp:
0
0
15
0
8
0
0
0
8
0
8
0
58
0
15
% D
% Glu:
0
8
50
0
8
8
0
0
0
0
0
0
8
8
0
% E
% Phe:
8
0
8
0
0
0
8
8
58
0
36
0
8
0
58
% F
% Gly:
65
8
0
0
0
0
0
8
0
0
8
22
0
65
0
% G
% His:
0
0
0
0
0
0
58
0
8
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
50
8
8
0
8
8
0
0
0
0
% K
% Leu:
8
15
0
58
0
15
0
0
8
8
8
0
15
0
15
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
8
0
8
8
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
58
0
8
0
0
0
8
0
0
8
0
% P
% Gln:
0
8
8
8
8
0
8
8
8
0
0
15
0
0
0
% Q
% Arg:
0
15
0
8
8
15
8
8
0
8
0
8
0
8
0
% R
% Ser:
8
0
0
0
8
0
0
0
0
58
0
0
0
0
8
% S
% Thr:
0
15
0
0
0
8
0
0
0
8
0
15
0
0
0
% T
% Val:
8
36
0
0
8
0
0
0
0
0
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
50
0
15
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _