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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRN3 All Species: 30.61
Human Site: S637 Identified Species: 56.11
UniProt: Q9NYV6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYV6 NP_060897.3 651 74107 S637 H F R S P S S S V G S P P V L
Chimpanzee Pan troglodytes XP_001143837 595 67943 S581 H F R S P S S S V G S P P V L
Rhesus Macaque Macaca mulatta XP_001108222 651 74080 S637 H F R S P S S S V G S P P M L
Dog Lupus familis XP_536965 651 74211 S630 H F R S P A S S V G S P P A L
Cat Felis silvestris
Mouse Mus musculus B2RS91 656 74499 S635 H F Q S P S S S V G S P P V L
Rat Rattus norvegicus NP_001129318 661 75125 S640 H F R S P S S S V G S P P V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518561 660 75690 S646 N F R S P S S S V G S P P I M
Chicken Gallus gallus
Frog Xenopus laevis NP_001107876 612 69642 F590 V E M T P G S F D S H L R S P
Zebra Danio Brachydanio rerio XP_706962 612 68744 S599 S H L Q S P R S V G S P P I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788084 611 70731 F593 V D K R P K N F D L S K S Q E
Honey Bee Apis mellifera XP_001122533 483 56793 N470 I L R D N I N N S E H R T T I
Nematode Worm Caenorhab. elegans P48322 654 75091 S639 T F S C G Q S S L I N Y S A T
Sea Urchin Strong. purpuratus XP_784172 374 42533 C361 L T P T S A A C I S P G F R S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.4 97.6 90.6 N.A. 86.8 85.4 N.A. 76 N.A. 66.8 59.9 N.A. 29.7 27.7 24.4 28.5
Protein Similarity: 100 89 99 94.7 N.A. 92.9 91.8 N.A. 86 N.A. 79.8 76 N.A. 48.8 46.3 42.8 40.7
P-Site Identity: 100 100 93.3 86.6 N.A. 93.3 100 N.A. 80 N.A. 13.3 40 N.A. 13.3 6.6 20 0
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 100 N.A. 20 46.6 N.A. 26.6 26.6 33.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 16 8 0 0 0 0 0 0 16 0 % A
% Cys: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 0 16 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 8 % E
% Phe: 0 62 0 0 0 0 0 16 0 0 0 0 8 0 0 % F
% Gly: 0 0 0 0 8 8 0 0 0 62 0 8 0 0 0 % G
% His: 47 8 0 0 0 0 0 0 0 0 16 0 0 0 0 % H
% Ile: 8 0 0 0 0 8 0 0 8 8 0 0 0 16 8 % I
% Lys: 0 0 8 0 0 8 0 0 0 0 0 8 0 0 0 % K
% Leu: 8 8 8 0 0 0 0 0 8 8 0 8 0 0 47 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 8 8 % M
% Asn: 8 0 0 0 8 0 16 8 0 0 8 0 0 0 0 % N
% Pro: 0 0 8 0 70 8 0 0 0 0 8 62 62 0 8 % P
% Gln: 0 0 8 8 0 8 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 54 8 0 0 8 0 0 0 0 8 8 8 0 % R
% Ser: 8 0 8 54 16 47 70 70 8 16 70 0 16 8 16 % S
% Thr: 8 8 0 16 0 0 0 0 0 0 0 0 8 8 8 % T
% Val: 16 0 0 0 0 0 0 0 62 0 0 0 0 31 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _