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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RRN3 All Species: 25.76
Human Site: Y235 Identified Species: 47.22
UniProt: Q9NYV6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYV6 NP_060897.3 651 74107 Y235 N L L R I S V Y F P T L R H E
Chimpanzee Pan troglodytes XP_001143837 595 67943 Q216 D A E E T A T Q T C G G T D S
Rhesus Macaque Macaca mulatta XP_001108222 651 74080 Y235 N L L R I S V Y F P T L R H E
Dog Lupus familis XP_536965 651 74211 Y235 N L L R I S V Y F P N L R H E
Cat Felis silvestris
Mouse Mus musculus B2RS91 656 74499 Y233 N L L R I S L Y F P T L R R E
Rat Rattus norvegicus NP_001129318 661 75125 Y233 N L L R I S L Y F P T L R R E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518561 660 75690 Y244 N L L R I S V Y F P S L R H E
Chicken Gallus gallus
Frog Xenopus laevis NP_001107876 612 69642 L219 E L V V E K L L K I D V S A S
Zebra Danio Brachydanio rerio XP_706962 612 68744 L219 E L I I S K M L M L D V S A P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788084 611 70731 Y218 N V L W L L E Y K P I F E E L
Honey Bee Apis mellifera XP_001122533 483 56793 F106 I D N L V E Q F K P E C R E E
Nematode Worm Caenorhab. elegans P48322 654 75091 Y222 N L I L M Q K Y I P A S I S K
Sea Urchin Strong. purpuratus XP_784172 374 42533
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.4 97.6 90.6 N.A. 86.8 85.4 N.A. 76 N.A. 66.8 59.9 N.A. 29.7 27.7 24.4 28.5
Protein Similarity: 100 89 99 94.7 N.A. 92.9 91.8 N.A. 86 N.A. 79.8 76 N.A. 48.8 46.3 42.8 40.7
P-Site Identity: 100 0 100 93.3 N.A. 86.6 86.6 N.A. 93.3 N.A. 6.6 6.6 N.A. 26.6 20 26.6 0
P-Site Similarity: 100 13.3 100 93.3 N.A. 93.3 93.3 N.A. 100 N.A. 26.6 26.6 N.A. 40 33.3 46.6 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 0 0 0 0 8 0 0 16 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % C
% Asp: 8 8 0 0 0 0 0 0 0 0 16 0 0 8 0 % D
% Glu: 16 0 8 8 8 8 8 0 0 0 8 0 8 16 54 % E
% Phe: 0 0 0 0 0 0 0 8 47 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 31 0 % H
% Ile: 8 0 16 8 47 0 0 0 8 8 8 0 8 0 0 % I
% Lys: 0 0 0 0 0 16 8 0 24 0 0 0 0 0 8 % K
% Leu: 0 70 54 16 8 8 24 16 0 8 0 47 0 0 8 % L
% Met: 0 0 0 0 8 0 8 0 8 0 0 0 0 0 0 % M
% Asn: 62 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 70 0 0 0 0 8 % P
% Gln: 0 0 0 0 0 8 8 8 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 47 0 0 0 0 0 0 0 0 54 16 0 % R
% Ser: 0 0 0 0 8 47 0 0 0 0 8 8 16 8 16 % S
% Thr: 0 0 0 0 8 0 8 0 8 0 31 0 8 0 0 % T
% Val: 0 8 8 8 8 0 31 0 0 0 0 16 0 0 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 62 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _