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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLK2
All Species:
26.67
Human Site:
T408
Identified Species:
58.67
UniProt:
Q9NYY3
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYY3
NP_006613.2
685
78237
T408
D
L
K
K
T
S
I
T
Q
Q
P
S
K
H
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001102530
669
76425
T392
D
L
K
K
T
S
I
T
Q
Q
P
S
K
H
R
Dog
Lupus familis
XP_535242
686
78191
T409
D
L
K
K
T
S
I
T
Q
Q
P
S
K
H
R
Cat
Felis silvestris
Mouse
Mus musculus
P53351
682
77794
T405
D
L
K
K
V
S
I
T
Q
Q
P
S
K
H
R
Rat
Rattus norvegicus
Q9R012
682
77902
T405
D
L
K
K
T
S
I
T
Q
Q
P
S
K
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_424739
671
76488
T396
D
L
K
K
T
S
I
T
Q
Q
P
Q
K
H
R
Frog
Xenopus laevis
P70032
598
68193
Q338
L
T
A
I
N
K
G
Q
D
S
P
L
V
E
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52304
576
66955
N316
R
K
P
L
M
E
M
N
G
I
R
P
D
D
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34331
649
73615
S376
E
P
E
D
A
Y
L
S
Q
L
F
H
Q
V
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P0C8M8
626
70215
S355
R
F
I
N
T
Q
G
S
N
M
F
G
S
E
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32562
705
81013
S419
P
F
L
P
H
S
L
S
P
G
G
T
K
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.3
97.6
N.A.
96.7
97
N.A.
N.A.
86.7
37.5
N.A.
N.A.
33.2
N.A.
27
N.A.
Protein Similarity:
100
N.A.
97.3
98.2
N.A.
97.5
97.8
N.A.
N.A.
91.2
57.3
N.A.
N.A.
54.8
N.A.
44.9
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
N.A.
93.3
6.6
N.A.
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
N.A.
93.3
13.3
N.A.
N.A.
6.6
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
31
N.A.
N.A.
31.7
N.A.
Protein Similarity:
N.A.
50.6
N.A.
N.A.
50
N.A.
P-Site Identity:
N.A.
6.6
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
0
0
10
0
0
0
0
10
0
0
0
10
10
0
% D
% Glu:
10
0
10
0
0
10
0
0
0
0
0
0
0
19
0
% E
% Phe:
0
19
0
0
0
0
0
0
0
0
19
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
19
0
10
10
10
10
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
10
0
55
0
% H
% Ile:
0
0
10
10
0
0
55
0
0
10
0
0
0
0
0
% I
% Lys:
0
10
55
55
0
10
0
0
0
0
0
0
64
0
28
% K
% Leu:
10
55
10
10
0
0
19
0
0
10
0
10
0
0
0
% L
% Met:
0
0
0
0
10
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
10
10
0
0
10
10
0
0
0
0
0
0
% N
% Pro:
10
10
10
10
0
0
0
0
10
0
64
10
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
10
64
55
0
10
10
10
0
% Q
% Arg:
19
0
0
0
0
0
0
0
0
0
10
0
0
0
55
% R
% Ser:
0
0
0
0
0
64
0
28
0
10
0
46
10
0
0
% S
% Thr:
0
10
0
0
55
0
0
55
0
0
0
10
0
0
10
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _