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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM18B
All Species:
37.88
Human Site:
S108
Identified Species:
52.08
UniProt:
Q9NYZ1
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYZ1
NP_057162.4
205
23648
S108
K
S
H
W
V
F
E
S
R
K
E
S
S
Q
E
Chimpanzee
Pan troglodytes
XP_511818
205
23460
S108
K
S
H
W
V
F
E
S
R
K
E
S
S
Q
E
Rhesus Macaque
Macaca mulatta
XP_001084390
205
23510
S108
K
S
H
W
V
F
E
S
R
K
E
S
S
Q
E
Dog
Lupus familis
XP_546636
205
23348
S108
K
S
H
W
V
F
E
S
R
K
A
S
A
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8T4
205
23286
S108
K
S
H
W
V
F
E
S
R
K
S
T
P
Q
D
Rat
Rattus norvegicus
NP_001101038
205
23216
S108
K
S
H
W
V
F
E
S
R
K
S
T
P
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510206
338
37065
A192
K
S
H
W
V
F
E
A
R
K
V
S
A
Q
G
Chicken
Gallus gallus
NP_001025870
207
23522
S108
R
S
H
W
K
F
E
S
R
K
V
S
A
Q
G
Frog
Xenopus laevis
NP_001088848
205
23372
E106
G
K
S
H
W
V
Y
E
S
R
K
A
A
Q
E
Zebra Danio
Brachydanio rerio
NP_001019599
203
22994
S104
K
S
H
W
V
F
E
S
R
K
A
S
G
N
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IQC1
223
25509
S112
V
S
H
W
V
F
E
S
K
N
S
E
S
Y
Q
Honey Bee
Apis mellifera
XP_392046
215
24433
S107
K
S
H
W
V
F
E
S
R
K
G
V
Q
Q
N
Nematode Worm
Caenorhab. elegans
Q18449
247
28650
S147
N
N
H
W
K
F
E
S
A
K
D
M
T
R
F
Sea Urchin
Strong. purpuratus
XP_780024
202
22997
K105
H
W
V
F
E
A
R
K
G
S
R
K
S
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEK2
186
21219
N101
Q
E
S
L
A
R
M
N
K
K
D
S
W
L
F
Baker's Yeast
Sacchar. cerevisiae
P38962
199
23129
I104
P
G
P
P
I
N
A
I
D
S
K
L
F
W
W
Red Bread Mold
Neurospora crassa
Q7SGB6
190
21130
D105
T
K
I
I
N
A
T
D
S
R
F
F
W
L
A
Conservation
Percent
Protein Identity:
100
97.5
97.5
92.1
N.A.
92.1
89.7
N.A.
48.8
79.7
75.6
70.7
N.A.
43.5
48.3
29.9
55.1
Protein Similarity:
100
98.5
99
96.5
N.A.
96
95.6
N.A.
55.6
89.8
88.2
85.8
N.A.
60.9
68.3
47.7
73.6
P-Site Identity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
73.3
66.6
13.3
73.3
N.A.
53.3
73.3
40
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
86.6
80
40
80
N.A.
66.6
73.3
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
28.2
33.6
Protein Similarity:
N.A.
N.A.
N.A.
48.2
47.8
50.2
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
12
6
6
6
0
12
6
24
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
6
6
0
12
0
0
0
12
% D
% Glu:
0
6
0
0
6
0
71
6
0
0
18
6
0
6
36
% E
% Phe:
0
0
0
6
0
71
0
0
0
0
6
6
6
0
12
% F
% Gly:
6
6
0
0
0
0
0
0
6
0
6
0
6
0
12
% G
% His:
6
0
71
6
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
6
6
0
0
6
0
0
0
0
0
0
0
% I
% Lys:
53
12
0
0
12
0
0
6
12
71
12
6
0
0
0
% K
% Leu:
0
0
0
6
0
0
0
0
0
0
0
6
0
12
0
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
6
0
0
0
% M
% Asn:
6
6
0
0
6
6
0
6
0
6
0
0
0
6
6
% N
% Pro:
6
0
6
6
0
0
0
0
0
0
0
0
12
0
0
% P
% Gln:
6
0
0
0
0
0
0
0
0
0
0
0
6
59
12
% Q
% Arg:
6
0
0
0
0
6
6
0
59
12
6
0
0
6
0
% R
% Ser:
0
65
12
0
0
0
0
65
12
12
18
48
30
0
0
% S
% Thr:
6
0
0
0
0
0
6
0
0
0
0
12
6
0
0
% T
% Val:
6
0
6
0
59
6
0
0
0
0
12
6
0
0
0
% V
% Trp:
0
6
0
71
6
0
0
0
0
0
0
0
12
6
6
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _