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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM18B
All Species:
36.06
Human Site:
S124
Identified Species:
49.58
UniProt:
Q9NYZ1
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYZ1
NP_057162.4
205
23648
S124
K
T
V
S
E
A
E
S
R
I
F
W
L
G
L
Chimpanzee
Pan troglodytes
XP_511818
205
23460
S124
K
T
V
S
E
A
E
S
R
I
F
W
L
G
L
Rhesus Macaque
Macaca mulatta
XP_001084390
205
23510
S124
K
T
V
S
E
A
E
S
R
I
F
W
L
G
L
Dog
Lupus familis
XP_546636
205
23348
S124
K
T
V
S
E
A
E
S
R
I
F
W
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8T4
205
23286
S124
K
T
I
S
E
A
E
S
R
I
F
W
L
G
L
Rat
Rattus norvegicus
NP_001101038
205
23216
S124
K
T
I
S
E
A
E
S
R
I
F
W
L
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510206
338
37065
S208
K
K
A
S
E
A
E
S
R
I
F
W
L
G
L
Chicken
Gallus gallus
NP_001025870
207
23522
S124
K
T
S
S
E
S
E
S
R
I
F
W
L
G
L
Frog
Xenopus laevis
NP_001088848
205
23372
S122
K
S
S
S
E
A
E
S
R
I
F
W
L
G
L
Zebra Danio
Brachydanio rerio
NP_001019599
203
22994
S120
S
A
S
R
S
S
N
S
E
S
R
I
F
W
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IQC1
223
25509
R128
R
V
N
K
N
E
Q
R
I
F
W
L
G
L
I
Honey Bee
Apis mellifera
XP_392046
215
24433
I123
I
N
T
T
E
A
R
I
F
W
L
A
L
I
L
Nematode Worm
Caenorhab. elegans
Q18449
247
28650
W163
T
I
D
R
R
V
F
W
L
G
L
V
V
G
P
Sea Urchin
Strong. purpuratus
XP_780024
202
22997
W121
G
L
E
S
K
I
F
W
F
G
L
V
V
C
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEK2
186
21219
A117
W
T
L
Y
L
A
A
A
A
W
F
I
L
G
V
Baker's Yeast
Sacchar. cerevisiae
P38962
199
23129
W120
M
Y
V
T
P
V
I
W
G
V
F
A
V
L
C
Red Bread Mold
Neurospora crassa
Q7SGB6
190
21130
V121
Y
A
Q
P
L
L
W
V
V
L
A
I
V
A
L
Conservation
Percent
Protein Identity:
100
97.5
97.5
92.1
N.A.
92.1
89.7
N.A.
48.8
79.7
75.6
70.7
N.A.
43.5
48.3
29.9
55.1
Protein Similarity:
100
98.5
99
96.5
N.A.
96
95.6
N.A.
55.6
89.8
88.2
85.8
N.A.
60.9
68.3
47.7
73.6
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
86.6
86.6
13.3
N.A.
0
26.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
93.3
93.3
20
N.A.
26.6
33.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
28.2
33.6
Protein Similarity:
N.A.
N.A.
N.A.
48.2
47.8
50.2
P-Site Identity:
N.A.
N.A.
N.A.
33.3
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
33.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
6
0
0
59
6
6
6
0
6
12
0
6
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
6
% C
% Asp:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
6
0
59
6
53
0
6
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
12
0
12
6
65
0
6
0
0
% F
% Gly:
6
0
0
0
0
0
0
0
6
12
0
0
6
65
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
6
6
12
0
0
6
6
6
6
53
0
18
0
6
6
% I
% Lys:
53
6
0
6
6
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
6
6
0
12
6
0
0
6
6
18
6
65
12
71
% L
% Met:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
6
6
0
6
0
6
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
6
6
0
0
0
0
0
0
0
0
0
12
% P
% Gln:
0
0
6
0
0
0
6
0
0
0
0
0
0
0
0
% Q
% Arg:
6
0
0
12
6
0
6
6
53
0
6
0
0
0
0
% R
% Ser:
6
6
18
59
6
12
0
59
0
6
0
0
0
0
0
% S
% Thr:
6
48
6
12
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
6
30
0
0
12
0
6
6
6
0
12
24
0
6
% V
% Trp:
6
0
0
0
0
0
6
18
0
12
6
53
0
6
0
% W
% Tyr:
6
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _