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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM18B All Species: 40
Human Site: S14 Identified Species: 55
UniProt: Q9NYZ1 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYZ1 NP_057162.4 205 23648 S14 N D D T E D V S L F D A E E E
Chimpanzee Pan troglodytes XP_511818 205 23460 S14 N D D T E D V S L F D A E E E
Rhesus Macaque Macaca mulatta XP_001084390 205 23510 S14 N D D T E D V S L F D A E E E
Dog Lupus familis XP_546636 205 23348 S14 N D D T E D V S L F D A E E E
Cat Felis silvestris
Mouse Mus musculus Q9D8T4 205 23286 S14 N D D T E D V S L F D A E E E
Rat Rattus norvegicus NP_001101038 205 23216 S14 N D D T E D V S L F D A E E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510206 338 37065 S98 N E D T E D V S L F D A D D D
Chicken Gallus gallus NP_001025870 207 23522 S14 S D D I E D V S L F D A D D E
Frog Xenopus laevis NP_001088848 205 23372 S14 N D E T E D V S L F D A E D E
Zebra Danio Brachydanio rerio NP_001019599 203 22994 F14 D D D D V S L F D A E E D S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQC1 223 25509 P18 L L D D D T I P F G E E D E M
Honey Bee Apis mellifera XP_392046 215 24433 T14 P L L M D D D T I A F G E E D
Nematode Worm Caenorhab. elegans Q18449 247 28650 G53 F E N D I S I G A T M T Q S Q
Sea Urchin Strong. purpuratus XP_780024 202 22997 G15 E D V A L D F G T E D E W K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8LEK2 186 21219 V11 N N Q I Q A P V E N Y A N P R
Baker's Yeast Sacchar. cerevisiae P38962 199 23129 S14 F Y N T I L K S S H P L L L S
Red Bread Mold Neurospora crassa Q7SGB6 190 21130 S15 G S L S W R L S S H P I T L L
Conservation
Percent
Protein Identity: 100 97.5 97.5 92.1 N.A. 92.1 89.7 N.A. 48.8 79.7 75.6 70.7 N.A. 43.5 48.3 29.9 55.1
Protein Similarity: 100 98.5 99 96.5 N.A. 96 95.6 N.A. 55.6 89.8 88.2 85.8 N.A. 60.9 68.3 47.7 73.6
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 73.3 73.3 86.6 13.3 N.A. 13.3 20 0 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 100 40 N.A. 40 46.6 33.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 30.7 28.2 33.6
Protein Similarity: N.A. N.A. N.A. 48.2 47.8 50.2
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 6.6
P-Site Similarity: N.A. N.A. N.A. 26.6 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 6 0 6 0 0 6 12 0 59 0 0 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 6 59 59 18 12 65 6 0 6 0 59 0 24 18 12 % D
% Glu: 6 12 6 0 53 0 0 0 6 6 12 18 48 48 48 % E
% Phe: 12 0 0 0 0 0 6 6 6 53 6 0 0 0 0 % F
% Gly: 6 0 0 0 0 0 0 12 0 6 0 6 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % H
% Ile: 0 0 0 12 12 0 12 0 6 0 0 6 0 0 0 % I
% Lys: 0 0 0 0 0 0 6 0 0 0 0 0 0 6 6 % K
% Leu: 6 12 12 0 6 6 12 0 53 0 0 6 6 12 6 % L
% Met: 0 0 0 6 0 0 0 0 0 0 6 0 0 0 6 % M
% Asn: 53 6 12 0 0 0 0 0 0 6 0 0 6 0 0 % N
% Pro: 6 0 0 0 0 0 6 6 0 0 12 0 0 6 0 % P
% Gln: 0 0 6 0 6 0 0 0 0 0 0 0 6 0 6 % Q
% Arg: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 6 % R
% Ser: 6 6 0 6 0 12 0 65 12 0 0 0 0 12 6 % S
% Thr: 0 0 0 53 0 6 0 6 6 6 0 6 6 0 0 % T
% Val: 0 0 6 0 6 0 53 6 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 6 0 0 0 0 0 0 0 6 0 0 % W
% Tyr: 0 6 0 0 0 0 0 0 0 0 6 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _