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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM18B
All Species:
37.88
Human Site:
S178
Identified Species:
52.08
UniProt:
Q9NYZ1
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYZ1
NP_057162.4
205
23648
S178
Y
I
R
C
K
V
R
S
R
K
H
L
T
S
M
Chimpanzee
Pan troglodytes
XP_511818
205
23460
S178
Y
I
R
C
K
V
G
S
R
K
N
L
T
S
M
Rhesus Macaque
Macaca mulatta
XP_001084390
205
23510
S178
Y
I
R
C
K
V
G
S
R
K
N
L
T
S
M
Dog
Lupus familis
XP_546636
205
23348
S178
Y
I
R
C
K
V
G
S
R
K
N
L
T
N
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8T4
205
23286
S178
Y
I
R
C
K
V
G
S
K
K
N
L
T
S
M
Rat
Rattus norvegicus
NP_001101038
205
23216
S178
Y
V
R
C
K
V
G
S
K
K
N
L
T
S
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510206
338
37065
S262
Y
M
R
C
K
V
G
S
K
K
N
L
T
S
V
Chicken
Gallus gallus
NP_001025870
207
23522
S178
Y
I
R
C
K
V
G
S
R
K
N
L
T
S
M
Frog
Xenopus laevis
NP_001088848
205
23372
S176
Y
I
K
C
K
V
G
S
R
K
N
L
T
S
I
Zebra Danio
Brachydanio rerio
NP_001019599
203
22994
A176
Y
V
R
C
K
V
G
A
R
T
N
L
K
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IQC1
223
25509
A181
Y
V
K
C
N
Y
G
A
N
K
D
L
N
S
A
Honey Bee
Apis mellifera
XP_392046
215
24433
N175
Y
V
K
C
K
M
G
N
D
K
N
I
S
A
A
Nematode Worm
Caenorhab. elegans
Q18449
247
28650
N213
Y
L
R
C
R
W
N
N
T
E
Q
M
T
S
Y
Sea Urchin
Strong. purpuratus
XP_780024
202
22997
S171
Y
V
R
C
K
I
T
S
R
K
E
L
S
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LEK2
186
21219
K160
T
K
C
K
K
D
A
K
K
Q
F
Q
Q
F
A
Baker's Yeast
Sacchar. cerevisiae
P38962
199
23129
G168
P
N
S
G
Q
S
D
G
Q
D
T
N
N
W
F
Red Bread Mold
Neurospora crassa
Q7SGB6
190
21130
N164
D
K
F
S
Q
A
S
N
I
A
G
T
A
F
S
Conservation
Percent
Protein Identity:
100
97.5
97.5
92.1
N.A.
92.1
89.7
N.A.
48.8
79.7
75.6
70.7
N.A.
43.5
48.3
29.9
55.1
Protein Similarity:
100
98.5
99
96.5
N.A.
96
95.6
N.A.
55.6
89.8
88.2
85.8
N.A.
60.9
68.3
47.7
73.6
P-Site Identity:
100
86.6
86.6
80
N.A.
80
73.3
N.A.
66.6
86.6
73.3
53.3
N.A.
33.3
26.6
33.3
66.6
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
80
N.A.
53.3
80
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
28.2
33.6
Protein Similarity:
N.A.
N.A.
N.A.
48.2
47.8
50.2
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
0
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
6
12
0
6
0
0
6
6
18
% A
% Cys:
0
0
6
83
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
6
6
0
6
6
6
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
6
6
0
0
0
0
% E
% Phe:
0
0
6
0
0
0
0
0
0
0
6
0
0
12
6
% F
% Gly:
0
0
0
6
0
0
65
6
0
0
6
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% H
% Ile:
0
42
0
0
0
6
0
0
6
0
0
6
0
0
6
% I
% Lys:
0
12
18
6
77
0
0
6
24
71
0
0
6
0
0
% K
% Leu:
0
6
0
0
0
0
0
0
0
0
0
71
0
0
0
% L
% Met:
0
6
0
0
0
6
0
0
0
0
0
6
0
0
53
% M
% Asn:
0
6
0
0
6
0
6
18
6
0
59
6
12
12
0
% N
% Pro:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
6
6
6
6
6
0
0
% Q
% Arg:
0
0
65
0
6
0
6
0
48
0
0
0
0
0
0
% R
% Ser:
0
0
6
6
0
6
6
59
0
0
0
0
12
65
6
% S
% Thr:
6
0
0
0
0
0
6
0
6
6
6
6
59
0
0
% T
% Val:
0
30
0
0
0
59
0
0
0
0
0
0
0
0
6
% V
% Trp:
0
0
0
0
0
6
0
0
0
0
0
0
0
6
0
% W
% Tyr:
83
0
0
0
0
6
0
0
0
0
0
0
0
0
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _