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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GTSE1 All Species: 13.64
Human Site: S477 Identified Species: 30
UniProt: Q9NYZ3 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NYZ3 NP_057510 720 76615 S477 S R A Q R P Q S C T S V G R V
Chimpanzee Pan troglodytes XP_515265 739 78374 S496 S R A Q R P Q S C M S V G R V
Rhesus Macaque Macaca mulatta XP_001110798 720 76069 S477 S R A Q R P Q S C T S V G R V
Dog Lupus familis XP_851086 844 89785 S592 H R A Q R P Q S C T S A G R V
Cat Felis silvestris
Mouse Mus musculus Q8R080 741 78733 R482 Q S W T P A S R V V S S T P V
Rat Rattus norvegicus Q3KR66 329 34559 L88 A N R L A A Q L E E C A L K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507852 731 77904 L478 C G G A L W G L G P D D P P P
Chicken Gallus gallus NP_001026503 724 77852 T478 L S V P A G Q T Q V P V K A G
Frog Xenopus laevis NP_001089367 724 77640 A477 R L R L P Q R A T G V S P D R
Zebra Danio Brachydanio rerio NP_001018461 728 77929 K477 P R I M K P K K L L T A C S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795811 658 69867 V417 P V F Q E K K V V P K R L L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.1 90.2 54.6 N.A. 56.5 21.2 N.A. 29 32.4 32.8 28.2 N.A. N.A. N.A. N.A. 20.8
Protein Similarity: 100 95.4 93.1 62.9 N.A. 67.8 30.6 N.A. 43.2 49.5 50 46.1 N.A. N.A. N.A. N.A. 35.8
P-Site Identity: 100 93.3 100 86.6 N.A. 13.3 6.6 N.A. 0 13.3 0 20 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 100 86.6 N.A. 13.3 20 N.A. 0 20 13.3 40 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 37 10 19 19 0 10 0 0 0 28 0 10 10 % A
% Cys: 10 0 0 0 0 0 0 0 37 0 10 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 10 0 10 10 % D
% Glu: 0 0 0 0 10 0 0 0 10 10 0 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 10 0 0 10 10 0 10 10 0 0 37 0 10 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 10 10 19 10 0 0 10 0 10 10 0 % K
% Leu: 10 10 0 19 10 0 0 19 10 10 0 0 19 10 0 % L
% Met: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 19 0 0 10 19 46 0 0 0 19 10 0 19 19 10 % P
% Gln: 10 0 0 46 0 10 55 0 10 0 0 0 0 0 0 % Q
% Arg: 10 46 19 0 37 0 10 10 0 0 0 10 0 37 10 % R
% Ser: 28 19 0 0 0 0 10 37 0 0 46 19 0 10 0 % S
% Thr: 0 0 0 10 0 0 0 10 10 28 10 0 10 0 0 % T
% Val: 0 10 10 0 0 0 0 10 19 19 10 37 0 0 55 % V
% Trp: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _