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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TECR All Species: 30
Human Site: Y189 Identified Species: 44
UniProt: Q9NZ01 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZ01 NP_612510.1 308 36034 Y189 P L Y T P P T Y G A Q Q V K L
Chimpanzee Pan troglodytes XP_512444 287 33341 I179 Q V K L A L A I F V I C Q L G
Rhesus Macaque Macaca mulatta XP_001112313 323 37461 Y204 P L Y T P P T Y G A Q Q V K L
Dog Lupus familis XP_852850 308 36016 Y189 P L Y T P P T Y G A Q Q V K L
Cat Felis silvestris
Mouse Mus musculus Q9CY27 308 36072 Y189 P L Y T P P T Y G V Q Q V K L
Rat Rattus norvegicus Q64232 308 36104 Y189 P L Y T P P T Y G V Q Q V K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512707 344 39629 Y225 P L Y T P P T Y G S E Q V K L
Chicken Gallus gallus XP_422331 293 34522 M185 Q I N F A V I M F L L C E A G
Frog Xenopus laevis NP_001085733 308 36132 Y189 P L Y T P P T Y G E D Q V K L
Zebra Danio Brachydanio rerio NP_958456 308 36259 Y189 P L Y T P P I Y G E Q Q I R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647836 302 34166 W189 S P C M C T V W G A L G A F A
Honey Bee Apis mellifera XP_001120311 300 34491 G189 K Q F Q F L V G L V T F V L C
Nematode Worm Caenorhab. elegans NP_495430 308 35091 F189 P L F T P P A F G D L Q V Y F
Sea Urchin Strong. purpuratus XP_781465 374 42420 D257 Y T P P S F G D S Q V Y F G L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38944 262 30616 V154 N W F W W R F V I G M V V F I
Baker's Yeast Sacchar. cerevisiae Q99190 310 36749 A189 Y G F P F G N A K L F K Y Y S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.8 93.8 99.3 N.A. 96.7 97.4 N.A. 84 64.9 90.5 85.3 N.A. 53.2 58.4 52.9 48.6
Protein Similarity: 100 83.4 94.7 100 N.A. 98.3 98.3 N.A. 87.5 76.9 95.4 94.1 N.A. 67.8 69.4 66.8 60.7
P-Site Identity: 100 0 100 100 N.A. 93.3 93.3 N.A. 86.6 0 86.6 73.3 N.A. 13.3 6.6 53.3 6.6
P-Site Similarity: 100 6.6 100 100 N.A. 93.3 93.3 N.A. 100 6.6 86.6 86.6 N.A. 20 13.3 66.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. 22 30.9 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 47.4 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 0 13 7 0 25 0 0 7 7 7 % A
% Cys: 0 0 7 0 7 0 0 0 0 0 0 13 0 0 7 % C
% Asp: 0 0 0 0 0 0 0 7 0 7 7 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 13 7 0 7 0 0 % E
% Phe: 0 0 25 7 13 7 7 7 13 0 7 7 7 13 7 % F
% Gly: 0 7 0 0 0 7 7 7 63 7 0 7 0 7 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 13 7 7 0 7 0 7 0 7 % I
% Lys: 7 0 7 0 0 0 0 0 7 0 0 7 0 44 0 % K
% Leu: 0 57 0 7 0 13 0 0 7 13 19 0 0 13 57 % L
% Met: 0 0 0 7 0 0 0 7 0 0 7 0 0 0 0 % M
% Asn: 7 0 7 0 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 57 7 7 13 57 57 0 0 0 0 0 0 0 0 0 % P
% Gln: 13 7 0 7 0 0 0 0 0 7 38 57 7 0 0 % Q
% Arg: 0 0 0 0 0 7 0 0 0 0 0 0 0 7 0 % R
% Ser: 7 0 0 0 7 0 0 0 7 7 0 0 0 0 7 % S
% Thr: 0 7 0 57 0 7 44 0 0 0 7 0 0 0 0 % T
% Val: 0 7 0 0 0 7 13 7 0 25 7 7 63 0 0 % V
% Trp: 0 7 0 7 7 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 13 0 50 0 0 0 0 50 0 0 0 7 7 13 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _