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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERAP1
All Species:
36.67
Human Site:
S721
Identified Species:
80.67
UniProt:
Q9NZ08
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZ08
NP_001035548.1
941
107235
S721
Q
T
W
T
D
E
G
S
V
S
E
R
M
L
R
Chimpanzee
Pan troglodytes
XP_527213
946
107116
S726
Q
T
W
T
D
E
G
S
V
S
E
R
M
L
R
Rhesus Macaque
Macaca mulatta
XP_001094669
946
108104
S726
Q
T
W
T
D
E
G
S
V
S
E
R
M
L
R
Dog
Lupus familis
XP_546015
1047
118941
S827
Q
T
W
T
D
E
G
S
V
T
E
R
M
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQH2
930
106581
S710
Q
T
W
T
D
E
G
S
V
S
E
R
M
L
R
Rat
Rattus norvegicus
Q9JJ22
930
106401
S710
Q
T
W
T
D
E
G
S
V
S
E
R
M
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512339
968
110122
S720
Q
S
W
S
D
E
G
S
V
S
E
R
M
L
R
Chicken
Gallus gallus
XP_001232418
1131
127728
S914
Q
L
W
S
D
E
G
S
V
S
E
R
M
L
R
Frog
Xenopus laevis
NP_001088429
1024
116161
E808
I
K
Q
T
W
M
D
E
G
T
L
A
E
R
Q
Zebra Danio
Brachydanio rerio
XP_692516
908
104241
S690
Q
S
W
S
D
N
G
S
V
S
E
R
M
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
T715
Q
D
A
L
D
N
F
T
K
Q
L
I
S
G
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
92.7
76.4
N.A.
84.2
83.8
N.A.
73.3
55.9
41.8
57
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.1
94.8
82.9
N.A.
91.8
91.5
N.A.
84.5
67.7
58.5
74
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
100
N.A.
86.6
86.6
6.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
20
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
91
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
73
0
10
0
0
82
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
82
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
0
10
0
0
0
0
0
0
19
0
0
82
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
82
0
10
% M
% Asn:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
91
0
10
0
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
82
0
10
82
% R
% Ser:
0
19
0
28
0
0
0
82
0
73
0
0
10
0
0
% S
% Thr:
0
55
0
64
0
0
0
10
0
19
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
82
0
0
0
0
0
0
% V
% Trp:
0
0
82
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _