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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERAP1
All Species:
16.97
Human Site:
T106
Identified Species:
37.33
UniProt:
Q9NZ08
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZ08
NP_001035548.1
941
107235
T106
H
L
Q
I
S
R
A
T
L
R
K
G
A
G
E
Chimpanzee
Pan troglodytes
XP_527213
946
107116
T111
H
L
Q
I
S
R
A
T
L
R
K
G
A
G
E
Rhesus Macaque
Macaca mulatta
XP_001094669
946
108104
T106
H
L
Q
I
S
R
A
T
L
R
K
G
A
G
E
Dog
Lupus familis
XP_546015
1047
118941
T212
L
L
Q
V
S
K
A
T
L
R
R
R
V
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQH2
930
106581
E107
A
G
E
M
L
S
E
E
P
L
K
V
L
E
Y
Rat
Rattus norvegicus
Q9JJ22
930
106401
E107
A
E
E
M
L
P
E
E
P
L
K
L
M
E
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512339
968
110122
S105
D
L
H
V
T
M
V
S
L
W
E
G
S
R
A
Chicken
Gallus gallus
XP_001232418
1131
127728
S204
G
V
D
A
A
R
S
S
R
R
A
D
P
R
R
Frog
Xenopus laevis
NP_001088429
1024
116161
V110
P
V
P
S
A
R
T
V
I
V
C
V
V
V
V
Zebra Danio
Brachydanio rerio
XP_692516
908
104241
E105
F
S
E
G
F
T
F
E
K
G
S
H
V
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
L109
L
P
D
N
V
V
P
L
H
Y
D
L
T
V
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
92.7
76.4
N.A.
84.2
83.8
N.A.
73.3
55.9
41.8
57
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.1
94.8
82.9
N.A.
91.8
91.5
N.A.
84.5
67.7
58.5
74
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
60
N.A.
6.6
6.6
N.A.
20
13.3
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
20
20
N.A.
53.3
40
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
29.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
10
19
0
37
0
0
0
10
0
28
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
10
0
19
0
0
0
0
0
0
0
10
10
0
0
0
% D
% Glu:
0
10
28
0
0
0
19
28
0
0
10
0
0
19
46
% E
% Phe:
10
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
10
0
0
0
0
0
10
0
37
0
37
0
% G
% His:
28
0
10
0
0
0
0
0
10
0
0
10
0
0
10
% H
% Ile:
0
0
0
28
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
0
10
0
46
0
0
0
0
% K
% Leu:
19
46
0
0
19
0
0
10
46
19
0
19
10
0
0
% L
% Met:
0
0
0
19
0
10
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
10
0
0
10
10
0
19
0
0
0
10
0
0
% P
% Gln:
0
0
37
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
46
0
0
10
46
10
10
0
19
10
% R
% Ser:
0
10
0
10
37
10
10
19
0
0
10
0
10
0
0
% S
% Thr:
0
0
0
0
10
10
10
37
0
0
0
0
10
0
0
% T
% Val:
0
19
0
19
10
10
10
10
0
10
0
19
28
28
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _