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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RTEL1
All Species:
19.7
Human Site:
S599
Identified Species:
36.11
UniProt:
Q9NZ71
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZ71
NP_057518.1
1219
133683
S599
P
R
S
K
G
S
F
S
E
T
I
S
A
Y
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113864
1596
173372
S596
P
R
S
K
G
S
F
S
E
T
I
S
A
Y
Y
Dog
Lupus familis
XP_543101
1581
171544
S597
P
R
N
K
G
G
F
S
E
V
V
D
A
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q0VGM9
1203
133748
S599
P
R
N
K
G
S
F
S
E
V
I
D
A
Y
Y
Rat
Rattus norvegicus
Q5RJZ1
1274
141760
S599
P
R
N
K
G
S
F
S
E
V
I
D
A
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508332
826
91181
S274
L
T
P
Y
D
L
A
S
G
L
D
V
I
N
Q
Chicken
Gallus gallus
XP_417435
1251
141584
A600
P
R
N
K
G
S
F
A
E
V
M
D
A
Y
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P0C928
1177
132786
T598
P
R
G
K
G
T
F
T
E
V
I
D
G
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W484
985
109665
Q432
K
Q
Q
G
A
K
Q
Q
G
G
W
L
G
K
G
Honey Bee
Apis mellifera
XP_396001
928
106015
F376
E
K
L
E
K
I
V
F
Y
L
T
T
T
S
T
Nematode Worm
Caenorhab. elegans
Q93575
994
112926
D442
V
K
L
V
D
R
V
D
P
K
T
V
A
R
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298143
749
84584
F197
L
V
N
I
G
R
T
F
G
P
C
P
Y
Y
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4M7
758
86217
V206
I
Q
F
A
N
V
I
V
Y
S
Y
Q
Y
L
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
71.1
60.5
N.A.
74.8
73
N.A.
40.2
59.4
N.A.
52.4
N.A.
33
33
28.5
N.A.
Protein Similarity:
100
N.A.
72.4
66.6
N.A.
83
80.6
N.A.
48.9
72.9
N.A.
70.5
N.A.
49.6
51
46.1
N.A.
P-Site Identity:
100
N.A.
100
66.6
N.A.
80
80
N.A.
6.6
66.6
N.A.
60
N.A.
0
0
6.6
N.A.
P-Site Similarity:
100
N.A.
100
80
N.A.
86.6
86.6
N.A.
6.6
86.6
N.A.
73.3
N.A.
6.6
20
13.3
N.A.
Percent
Protein Identity:
27.8
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
39.3
N.A.
N.A.
34.7
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
8
8
0
0
0
0
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
0
8
0
0
8
39
0
0
0
% D
% Glu:
8
0
0
8
0
0
0
0
54
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
54
16
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
62
8
0
0
24
8
0
0
16
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
8
8
0
0
0
39
0
8
0
8
% I
% Lys:
8
16
0
54
8
8
0
0
0
8
0
0
0
8
0
% K
% Leu:
16
0
16
0
0
8
0
0
0
16
0
8
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
39
0
8
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
54
0
8
0
0
0
0
0
8
8
0
8
0
0
0
% P
% Gln:
0
16
8
0
0
0
8
8
0
0
0
8
0
0
8
% Q
% Arg:
0
54
0
0
0
16
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
16
0
0
39
0
47
0
8
0
16
0
8
0
% S
% Thr:
0
8
0
0
0
8
8
8
0
16
16
8
8
0
8
% T
% Val:
8
8
0
8
0
8
16
8
0
39
8
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
16
0
8
0
16
62
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _