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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RTEL1
All Species:
15.15
Human Site:
T1177
Identified Species:
27.78
UniProt:
Q9NZ71
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZ71
NP_057518.1
1219
133683
T1177
R
S
E
K
T
G
K
T
Q
S
K
I
S
S
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113864
1596
173372
T1175
R
S
E
K
P
G
K
T
Q
S
E
I
S
T
F
Dog
Lupus familis
XP_543101
1581
171544
T1181
Q
Q
E
K
P
G
T
T
Q
S
K
I
S
A
F
Cat
Felis silvestris
Mouse
Mus musculus
Q0VGM9
1203
133748
T1159
M
S
K
K
P
E
K
T
Q
S
K
I
S
S
F
Rat
Rattus norvegicus
Q5RJZ1
1274
141760
T1176
T
S
K
K
P
E
K
T
Q
S
K
I
S
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508332
826
91181
R785
A
E
R
P
R
H
H
R
V
V
V
D
G
E
R
Chicken
Gallus gallus
XP_417435
1251
141584
N1193
K
S
E
V
P
E
K
N
E
G
E
T
S
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P0C928
1177
132786
L1136
R
K
Q
F
G
E
L
L
K
S
L
T
G
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9W484
985
109665
F943
K
N
G
T
Y
E
S
F
Q
A
L
M
A
I
L
Honey Bee
Apis mellifera
XP_396001
928
106015
D887
K
L
S
L
S
E
T
D
Y
K
I
F
A
T
M
Nematode Worm
Caenorhab. elegans
Q93575
994
112926
F953
S
I
R
W
D
E
V
F
Q
R
F
R
P
I
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298143
749
84584
K708
P
H
I
K
C
H
S
K
F
G
D
V
V
F
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W4M7
758
86217
A717
T
D
M
A
I
H
I
A
R
E
F
L
R
K
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
71.1
60.5
N.A.
74.8
73
N.A.
40.2
59.4
N.A.
52.4
N.A.
33
33
28.5
N.A.
Protein Similarity:
100
N.A.
72.4
66.6
N.A.
83
80.6
N.A.
48.9
72.9
N.A.
70.5
N.A.
49.6
51
46.1
N.A.
P-Site Identity:
100
N.A.
80
66.6
N.A.
73.3
73.3
N.A.
0
33.3
N.A.
13.3
N.A.
6.6
0
13.3
N.A.
P-Site Similarity:
100
N.A.
93.3
80
N.A.
80
80
N.A.
0
53.3
N.A.
33.3
N.A.
40
26.6
13.3
N.A.
Percent
Protein Identity:
27.8
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
39.3
N.A.
N.A.
34.7
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
8
0
8
0
0
16
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
0
0
8
0
0
8
8
0
0
8
% D
% Glu:
0
8
31
0
0
54
0
0
8
8
16
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
0
16
8
0
16
8
0
8
47
% F
% Gly:
0
0
8
0
8
24
0
0
0
16
0
0
16
0
0
% G
% His:
0
8
0
0
0
24
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
8
0
0
0
8
39
0
16
0
% I
% Lys:
24
8
16
47
0
0
39
8
8
8
31
0
0
8
0
% K
% Leu:
0
8
0
8
0
0
8
8
0
0
16
8
0
0
8
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
16
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% N
% Pro:
8
0
0
8
39
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
8
8
8
0
0
0
0
0
54
0
0
0
0
0
0
% Q
% Arg:
24
0
16
0
8
0
0
8
8
8
0
8
8
0
8
% R
% Ser:
8
39
8
0
8
0
16
0
0
47
0
0
47
31
8
% S
% Thr:
16
0
0
8
8
0
16
39
0
0
0
16
0
16
8
% T
% Val:
0
0
0
8
0
0
8
0
8
8
8
8
8
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _