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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLIC5
All Species:
9.09
Human Site:
S139
Identified Species:
22.22
UniProt:
Q9NZA1
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZA1
NP_001107558.1
410
46503
S139
K
E
D
L
P
S
P
S
S
F
T
I
Q
H
S
Chimpanzee
Pan troglodytes
XP_001142911
410
46498
S139
K
E
D
L
P
S
P
S
S
F
T
I
Q
H
S
Rhesus Macaque
Macaca mulatta
XP_001101512
412
46560
S139
K
E
D
L
P
S
P
S
S
F
T
I
Q
H
S
Dog
Lupus familis
XP_538943
406
45538
A138
G
E
D
L
P
S
P
A
N
F
T
I
Q
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXK9
251
28268
Rat
Rattus norvegicus
Q9EPT8
251
28280
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511421
321
36053
Q63
R
L
G
R
S
D
I
Q
E
Q
G
A
L
P
G
Chicken
Gallus gallus
XP_420060
389
43798
P131
S
Q
S
T
S
T
S
P
T
S
L
K
F
P
H
Frog
Xenopus laevis
NP_001080333
250
28265
Zebra Danio
Brachydanio rerio
NP_998062
408
45237
G139
A
F
S
L
P
E
D
G
S
P
E
P
E
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
95.3
77.8
N.A.
58.7
58.5
N.A.
60.7
61.7
52.9
55.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.2
96.1
84.3
N.A.
60.7
60.4
N.A.
66.3
70.7
58
67.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
0
0
N.A.
0
0
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
0
0
N.A.
6.6
20
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
40
0
0
10
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
40
0
0
0
10
0
0
10
0
10
0
10
20
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
40
0
0
10
0
0
% F
% Gly:
10
0
10
0
0
0
0
10
0
0
10
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
10
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
40
0
0
10
% I
% Lys:
30
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
10
0
50
0
0
0
0
0
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
50
0
40
10
0
10
0
10
0
20
0
% P
% Gln:
0
10
0
0
0
0
0
10
0
10
0
0
40
0
0
% Q
% Arg:
10
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
20
0
20
40
10
30
40
10
0
0
0
0
30
% S
% Thr:
0
0
0
10
0
10
0
0
10
0
40
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _