Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 6.97
Human Site: S415 Identified Species: 11.79
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 S415 Q G L R P R M S F S S Q V A T
Chimpanzee Pan troglodytes XP_001173932 638 70317 S417 Q G L R P R M S F S S Q V A T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 R413 H V Q G I R H R V S F S N R M
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 C415 R N P S A R Q C L S D Q M A S
Rat Rattus norvegicus NP_001100351 480 53567 D285 L E K L P E E D S S T A K A F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 L376 A R P R P V P L L M T P P S T
Chicken Gallus gallus XP_419475 724 79312 P486 M G Q P P P S P G I L Q T Q L
Frog Xenopus laevis NP_001086201 389 43733 I194 V P P K F E F I V R R K G F H
Zebra Danio Brachydanio rerio NP_001099130 402 45478 I207 V P A K F E F I T R R K G F H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 A370 K K Q H A D A A P R L H H H L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 S397 R G L T P V T S A S S I L V H
Sea Urchin Strong. purpuratus XP_783948 669 74015 L446 H V L P V S I L F N H G A R S
Poplar Tree Populus trichocarpa XP_002314219 355 40047 L160 V P A K F E F L T R R K G H E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 L195 V P A K F E F L T R R K G H D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 100 N.A. 13.3 N.A. 26.6 20 N.A. 20 20 0 0 N.A. 0 N.A. 40 13.3
P-Site Similarity: 100 100 N.A. 13.3 N.A. 46.6 26.6 N.A. 33.3 20 13.3 13.3 N.A. 13.3 N.A. 53.3 33.3
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 22 0 15 0 8 8 8 0 0 8 8 29 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 0 0 8 0 0 0 8 % D
% Glu: 0 8 0 0 0 36 8 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 29 0 29 0 22 0 8 0 0 15 8 % F
% Gly: 0 29 0 8 0 0 0 0 8 0 0 8 29 0 0 % G
% His: 15 0 0 8 0 0 8 0 0 0 8 8 8 22 22 % H
% Ile: 0 0 0 0 8 0 8 15 0 8 0 8 0 0 0 % I
% Lys: 8 8 8 29 0 0 0 0 0 0 0 29 8 0 0 % K
% Leu: 8 0 29 8 0 0 0 29 15 0 15 0 8 0 15 % L
% Met: 8 0 0 0 0 0 15 0 0 8 0 0 8 0 8 % M
% Asn: 0 8 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 0 29 22 15 43 8 8 8 8 0 0 8 8 0 0 % P
% Gln: 15 0 22 0 0 0 8 0 0 0 0 29 0 8 0 % Q
% Arg: 15 8 0 22 0 29 0 8 0 36 29 0 0 15 0 % R
% Ser: 0 0 0 8 0 8 8 22 8 43 22 8 0 8 15 % S
% Thr: 0 0 0 8 0 0 8 0 22 0 15 0 8 0 22 % T
% Val: 29 15 0 0 8 15 0 0 15 0 0 0 15 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _