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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 10.91
Human Site: S417 Identified Species: 18.46
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 S417 L R P R M S F S S Q V A T L W
Chimpanzee Pan troglodytes XP_001173932 638 70317 S419 L R P R M S F S S Q V A T L W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 S415 Q G I R H R V S F S N R M S T
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 S417 P S A R Q C L S D Q M A S L W
Rat Rattus norvegicus NP_001100351 480 53567 S287 K L P E E D S S T A K A F K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 M378 P R P V P L L M T P P S T C S
Chicken Gallus gallus XP_419475 724 79312 I488 Q P P P S P G I L Q T Q L R G
Frog Xenopus laevis NP_001086201 389 43733 R196 P K F E F I V R R K G F H K V
Zebra Danio Brachydanio rerio NP_001099130 402 45478 R209 A K F E F I T R R K G F H K V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 R372 Q H A D A A P R L H H H L H P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 S399 L T P V T S A S S I L V H L P
Sea Urchin Strong. purpuratus XP_783948 669 74015 N448 L P V S I L F N H G A R S Y K
Poplar Tree Populus trichocarpa XP_002314219 355 40047 R162 A K F E F L T R R K G H E R V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 R197 A K F E F L T R R K G H D R V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 100 N.A. 13.3 N.A. 40 20 N.A. 20 13.3 0 0 N.A. 0 N.A. 40 13.3
P-Site Similarity: 100 100 N.A. 13.3 N.A. 53.3 26.6 N.A. 33.3 13.3 13.3 13.3 N.A. 6.6 N.A. 46.6 33.3
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 0 15 0 8 8 8 0 0 8 8 29 0 0 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 8 0 8 0 0 8 0 0 0 8 0 0 % D
% Glu: 0 0 0 36 8 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 29 0 29 0 22 0 8 0 0 15 8 0 0 % F
% Gly: 0 8 0 0 0 0 8 0 0 8 29 0 0 0 8 % G
% His: 0 8 0 0 8 0 0 0 8 8 8 22 22 8 0 % H
% Ile: 0 0 8 0 8 15 0 8 0 8 0 0 0 0 8 % I
% Lys: 8 29 0 0 0 0 0 0 0 29 8 0 0 22 8 % K
% Leu: 29 8 0 0 0 29 15 0 15 0 8 0 15 29 0 % L
% Met: 0 0 0 0 15 0 0 8 0 0 8 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 0 % N
% Pro: 22 15 43 8 8 8 8 0 0 8 8 0 0 0 15 % P
% Gln: 22 0 0 0 8 0 0 0 0 29 0 8 0 0 0 % Q
% Arg: 0 22 0 29 0 8 0 36 29 0 0 15 0 22 0 % R
% Ser: 0 8 0 8 8 22 8 43 22 8 0 8 15 8 8 % S
% Thr: 0 8 0 0 8 0 22 0 15 0 8 0 22 0 8 % T
% Val: 0 0 8 15 0 0 15 0 0 0 15 8 0 0 29 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _