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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 10.91
Human Site: S442 Identified Species: 18.46
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 S442 L A Q Q R L G S G S F Q R H Y
Chimpanzee Pan troglodytes XP_001173932 638 70317 S444 L A Q Q R L G S G F F Q R H Y
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 S440 P P L G Q R W S N S P Q R H C
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 S442 L S Q Q C L G S G S P Q R H Y
Rat Rattus norvegicus NP_001100351 480 53567 C312 T S M S E H F C G T C N R L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 R403 R W V L V I P R A G P G R A P
Chicken Gallus gallus XP_419475 724 79312 E513 T F D K K C L E A S P V G Q V
Frog Xenopus laevis NP_001086201 389 43733 N221 G Y N P V K V N C V V M R G L
Zebra Danio Brachydanio rerio NP_001099130 402 45478 N234 G Y N P V K V N C V V M R G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 N397 R L Q L Q A R N Y S Q L T H V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 S424 S S R H F F I S Q I R C F S T
Sea Urchin Strong. purpuratus XP_783948 669 74015 A473 S S T M S C M A K D S S D G D
Poplar Tree Populus trichocarpa XP_002314219 355 40047 N187 G Y N P V K V N C V V M R G F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 N222 G Y N P V K V N C V I M R G L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 93.3 N.A. 33.3 N.A. 80 13.3 N.A. 6.6 6.6 6.6 6.6 N.A. 20 N.A. 6.6 0
P-Site Similarity: 100 93.3 N.A. 40 N.A. 86.6 26.6 N.A. 13.3 20 13.3 13.3 N.A. 33.3 N.A. 20 13.3
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 0 8 0 8 15 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 8 15 0 8 29 0 8 8 0 0 8 % C
% Asp: 0 0 8 0 0 0 0 0 0 8 0 0 8 0 8 % D
% Glu: 0 0 0 0 8 0 0 8 0 0 0 0 0 0 0 % E
% Phe: 0 8 0 0 8 8 8 0 0 8 15 0 8 0 8 % F
% Gly: 29 0 0 8 0 0 22 0 29 8 0 8 8 36 0 % G
% His: 0 0 0 8 0 8 0 0 0 0 0 0 0 36 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 8 8 0 0 0 0 % I
% Lys: 0 0 0 8 8 29 0 0 8 0 0 0 0 0 0 % K
% Leu: 22 8 8 15 0 22 8 0 0 0 0 8 0 8 22 % L
% Met: 0 0 8 8 0 0 8 0 0 0 0 29 0 0 0 % M
% Asn: 0 0 29 0 0 0 0 36 8 0 0 8 0 0 0 % N
% Pro: 8 8 0 29 0 0 8 0 0 0 29 0 0 0 8 % P
% Gln: 0 0 29 22 15 0 0 0 8 0 8 29 0 8 0 % Q
% Arg: 15 0 8 0 15 8 8 8 0 0 8 0 72 0 8 % R
% Ser: 15 29 0 8 8 0 0 36 0 36 8 8 0 8 0 % S
% Thr: 15 0 8 0 0 0 0 0 0 8 0 0 8 0 8 % T
% Val: 0 0 8 0 36 0 29 0 0 29 22 8 0 0 15 % V
% Trp: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 29 0 0 0 0 0 0 8 0 0 0 0 0 22 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _