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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 7.88
Human Site: S459 Identified Species: 13.33
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 S459 R A D S D A N S K C L S P G S
Chimpanzee Pan troglodytes XP_001173932 638 70317 S461 R A D L D A N S K C L S P G S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 P457 H L D S D A N P K C L S A V S
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 S459 Y P D P D T H S K C L S T G S
Rat Rattus norvegicus NP_001100351 480 53567 C329 A D G N L K V C L F G N S E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 D420 H R C S G P K D S D P D A A C
Chicken Gallus gallus XP_419475 724 79312 N530 D C Q S K E A N T G S E F S N
Frog Xenopus laevis NP_001086201 389 43733 E238 D E L L D F V E L T E K Q P L
Zebra Danio Brachydanio rerio NP_001099130 402 45478 S251 D E L V D F V S L T E R K P L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 D414 Q G K A Q M V D V G A K P S T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 L441 S V S S I T H L L T H V D N N
Sea Urchin Strong. purpuratus XP_783948 669 74015 G490 K D S S D G D G S K D S S N G
Poplar Tree Populus trichocarpa XP_002314219 355 40047 E204 D E I C D F V E L T H N K P I
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 E239 D E I C D F V E L T R D K P I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 93.3 N.A. 66.6 N.A. 60 0 N.A. 6.6 6.6 6.6 13.3 N.A. 6.6 N.A. 6.6 20
P-Site Similarity: 100 93.3 N.A. 66.6 N.A. 66.6 13.3 N.A. 6.6 20 6.6 13.3 N.A. 26.6 N.A. 20 33.3
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 0 8 0 22 8 0 0 0 8 0 15 8 0 % A
% Cys: 0 8 8 15 0 0 0 8 0 29 0 0 0 0 8 % C
% Asp: 36 15 29 0 65 0 8 15 0 8 8 15 8 0 0 % D
% Glu: 0 29 0 0 0 8 0 22 0 0 15 8 0 8 0 % E
% Phe: 0 0 0 0 0 29 0 0 0 8 0 0 8 0 0 % F
% Gly: 0 8 8 0 8 8 0 8 0 15 8 0 0 22 8 % G
% His: 15 0 0 0 0 0 15 0 0 0 15 0 0 0 0 % H
% Ile: 0 0 15 0 8 0 0 0 0 0 0 0 0 0 15 % I
% Lys: 8 0 8 0 8 8 8 0 29 8 0 15 22 0 0 % K
% Leu: 0 8 15 15 8 0 0 8 43 0 29 0 0 0 15 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 22 8 0 0 0 15 0 15 15 % N
% Pro: 0 8 0 8 0 8 0 8 0 0 8 0 22 29 0 % P
% Gln: 8 0 8 0 8 0 0 0 0 0 0 0 8 0 0 % Q
% Arg: 15 8 0 0 0 0 0 0 0 0 8 8 0 0 0 % R
% Ser: 8 0 15 43 0 0 0 29 15 0 8 36 15 15 29 % S
% Thr: 0 0 0 0 0 15 0 0 8 36 0 0 8 0 8 % T
% Val: 0 8 0 8 0 0 43 0 8 0 0 8 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _