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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 11.52
Human Site: S466 Identified Species: 19.49
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 S466 S K C L S P G S W A S A A P S
Chimpanzee Pan troglodytes XP_001173932 638 70317 S468 S K C L S P G S W A S A A P S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 S464 P K C L S A V S G A P A T P S
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 S466 S K C L S T G S Q A P D A P S
Rat Rattus norvegicus NP_001100351 480 53567 V336 C L F G N S E V S L R D H L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 C427 D S D P D A A C L P T G G P P
Chicken Gallus gallus XP_419475 724 79312 N537 N T G S E F S N R N S G S C T
Frog Xenopus laevis NP_001086201 389 43733 L245 E L T E K Q P L E V R F I E Y
Zebra Danio Brachydanio rerio NP_001099130 402 45478 L258 S L T E R K P L D V R F I E Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 T421 D V G A K P S T T R L A R A E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 N448 L L T H V D N N G N A K Q V D
Sea Urchin Strong. purpuratus XP_783948 669 74015 G497 G S K D S S N G D R S K D S S
Poplar Tree Populus trichocarpa XP_002314219 355 40047 I211 E L T H N K P I N V R F I E F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 I246 E L T R D K P I N V R F I E F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 100 N.A. 60 N.A. 73.3 0 N.A. 6.6 6.6 0 6.6 N.A. 13.3 N.A. 0 20
P-Site Similarity: 100 100 N.A. 60 N.A. 73.3 6.6 N.A. 13.3 33.3 0 6.6 N.A. 20 N.A. 13.3 20
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 15 8 0 0 29 8 29 22 8 0 % A
% Cys: 8 0 29 0 0 0 0 8 0 0 0 0 0 8 0 % C
% Asp: 15 0 8 8 15 8 0 0 15 0 0 15 8 0 8 % D
% Glu: 22 0 0 15 8 0 8 0 8 0 0 0 0 29 8 % E
% Phe: 0 0 8 0 0 8 0 0 0 0 0 29 0 0 15 % F
% Gly: 8 0 15 8 0 0 22 8 15 0 0 15 8 0 0 % G
% His: 0 0 0 15 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 0 15 0 0 0 0 29 0 0 % I
% Lys: 0 29 8 0 15 22 0 0 0 0 0 15 0 0 0 % K
% Leu: 8 43 0 29 0 0 0 15 8 8 8 0 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 15 0 15 15 15 15 0 0 0 0 0 % N
% Pro: 8 0 0 8 0 22 29 0 0 8 15 0 0 36 8 % P
% Gln: 0 0 0 0 0 8 0 0 8 0 0 0 8 0 0 % Q
% Arg: 0 0 0 8 8 0 0 0 8 15 36 0 8 0 8 % R
% Ser: 29 15 0 8 36 15 15 29 8 0 29 0 8 8 36 % S
% Thr: 0 8 36 0 0 8 0 8 8 0 8 0 8 0 8 % T
% Val: 0 8 0 0 8 0 8 8 0 29 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _