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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 15.15
Human Site: S473 Identified Species: 25.64
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 S473 S W A S A A P S G P Q L T S E
Chimpanzee Pan troglodytes XP_001173932 638 70317 S475 S W A S A A P S G P Q L T S E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 S471 S G A P A T P S G P L P T S D
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 S473 S Q A P D A P S G P G P T S N
Rat Rattus norvegicus NP_001100351 480 53567 R343 V S L R D H L R A G A S E E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 P434 C L P T G G P P G S P P G A D
Chicken Gallus gallus XP_419475 724 79312 T544 N R N S G S C T K I R R A S D
Frog Xenopus laevis NP_001086201 389 43733 Y252 L E V R F I E Y M P F D G N K
Zebra Danio Brachydanio rerio NP_001099130 402 45478 Y265 L D V R F I E Y M P F N G N R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 E428 T T R L A R A E A T V Q V G E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 D455 N G N A K Q V D V S Q K D T S
Sea Urchin Strong. purpuratus XP_783948 669 74015 S504 G D R S K D S S D G D R S S S
Poplar Tree Populus trichocarpa XP_002314219 355 40047 F218 I N V R F I E F M P F D G N V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 F253 I N V R F I E F M P F D G N V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 100 N.A. 60 N.A. 60 6.6 N.A. 13.3 13.3 6.6 6.6 N.A. 13.3 N.A. 6.6 20
P-Site Similarity: 100 100 N.A. 66.6 N.A. 60 6.6 N.A. 33.3 46.6 20 13.3 N.A. 20 N.A. 26.6 26.6
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 29 8 29 22 8 0 15 0 8 0 8 8 0 % A
% Cys: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 0 0 15 8 0 8 8 0 8 22 8 0 22 % D
% Glu: 0 8 0 0 0 0 29 8 0 0 0 0 8 8 29 % E
% Phe: 0 0 0 0 29 0 0 15 0 0 29 0 0 0 0 % F
% Gly: 8 15 0 0 15 8 0 0 36 15 8 0 36 8 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 15 0 0 0 0 29 0 0 0 8 0 0 0 0 0 % I
% Lys: 0 0 0 0 15 0 0 0 8 0 0 8 0 0 8 % K
% Leu: 15 8 8 8 0 0 8 0 0 0 8 15 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 29 0 0 0 0 0 0 % M
% Asn: 15 15 15 0 0 0 0 0 0 0 0 8 0 29 8 % N
% Pro: 0 0 8 15 0 0 36 8 0 58 8 22 0 0 0 % P
% Gln: 0 8 0 0 0 8 0 0 0 0 22 8 0 0 0 % Q
% Arg: 0 8 15 36 0 8 0 8 0 0 8 15 0 0 8 % R
% Ser: 29 8 0 29 0 8 8 36 0 15 0 8 8 43 15 % S
% Thr: 8 8 0 8 0 8 0 8 0 8 0 0 29 8 0 % T
% Val: 8 0 29 0 0 0 8 0 8 0 8 0 8 0 15 % V
% Trp: 0 15 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _