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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 26.36
Human Site: T270 Identified Species: 44.62
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 T270 S Y K E M L D T V R Q Q W P E
Chimpanzee Pan troglodytes XP_001173932 638 70317 T270 S Y K E M L D T V R Q Q W P E
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 T270 S Y K E M L D T L Q Q Q W P E
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 T270 S Y K E M L D T I R Q R W P G
Rat Rattus norvegicus NP_001100351 480 53567 T154 G L R T I G V T T N G I N L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 T240 S Y K E M L D T I Q G R W P E
Chicken Gallus gallus XP_419475 724 79312 T316 S Y K E M L D T I K Q R W P E
Frog Xenopus laevis NP_001086201 389 43733 A63 E H P V P F S A F L T D S F G
Zebra Danio Brachydanio rerio NP_001099130 402 45478 Q76 K D V L P F S Q F L T D S F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 F234 E I C D F V E F T R N R P V D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 N257 E F M P F G G N E F K N D N F
Sea Urchin Strong. purpuratus XP_783948 669 74015 T295 T K D E I V Q T I R G R F P D
Poplar Tree Populus trichocarpa XP_002314219 355 40047 D29 M S T N L A S D M L I D S F G
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 D64 I K D N P V S D M L I D K F G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 100 N.A. 86.6 N.A. 80 6.6 N.A. 73.3 80 0 0 N.A. 6.6 N.A. 0 26.6
P-Site Similarity: 100 100 N.A. 100 N.A. 93.3 20 N.A. 93.3 100 6.6 0 N.A. 40 N.A. 13.3 73.3
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 15 8 0 0 43 15 0 0 0 29 8 0 15 % D
% Glu: 22 0 0 50 0 0 8 0 8 0 0 0 0 0 36 % E
% Phe: 0 8 0 0 15 15 0 8 15 8 0 0 8 29 8 % F
% Gly: 8 0 0 0 0 15 8 0 0 0 22 0 0 0 36 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 15 0 0 0 29 0 15 8 0 0 0 % I
% Lys: 8 15 43 0 0 0 0 0 0 8 8 0 8 0 0 % K
% Leu: 0 8 0 8 8 43 0 0 8 29 0 0 0 8 0 % L
% Met: 8 0 8 0 43 0 0 0 15 0 0 0 0 0 0 % M
% Asn: 0 0 0 15 0 0 0 8 0 8 8 8 8 8 0 % N
% Pro: 0 0 8 8 22 0 0 0 0 0 0 0 8 50 0 % P
% Gln: 0 0 0 0 0 0 8 8 0 15 36 22 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 36 0 36 0 0 0 % R
% Ser: 43 8 0 0 0 0 29 0 0 0 0 0 22 0 0 % S
% Thr: 8 0 8 8 0 0 0 58 15 0 15 0 0 0 0 % T
% Val: 0 0 8 8 0 22 8 0 15 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 43 0 0 % W
% Tyr: 0 43 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _