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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 11.52
Human Site: T450 Identified Species: 19.49
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 T450 G S F Q R H Y T S R A D S D A
Chimpanzee Pan troglodytes XP_001173932 638 70317 T452 G F F Q R H Y T S R A D L D A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 S448 N S P Q R H C S S H L D S D A
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 S450 G S P Q R H Y S S Y P D P D T
Rat Rattus norvegicus NP_001100351 480 53567 I320 G T C N R L R I T A D G N L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 L411 A G P G R A P L R H R C S G P
Chicken Gallus gallus XP_419475 724 79312 S521 A S P V G Q V S V D C Q S K E
Frog Xenopus laevis NP_001086201 389 43733 N229 C V V M R G L N E D E L L D F
Zebra Danio Brachydanio rerio NP_001099130 402 45478 N242 C V V M R G L N E D E L V D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 D405 Y S Q L T H V D G Q G K A Q M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 T432 Q I R C F S T T Y S V S S I T
Sea Urchin Strong. purpuratus XP_783948 669 74015 R481 K D S S D G D R S K D S S D G
Poplar Tree Populus trichocarpa XP_002314219 355 40047 N195 C V V M R G F N D D E I C D F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 N230 C V I M R G L N D D E I C D F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 86.6 N.A. 60 N.A. 60 13.3 N.A. 13.3 13.3 13.3 13.3 N.A. 13.3 N.A. 13.3 20
P-Site Similarity: 100 86.6 N.A. 66.6 N.A. 66.6 33.3 N.A. 13.3 20 13.3 13.3 N.A. 26.6 N.A. 13.3 26.6
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 8 0 0 0 8 15 0 8 0 22 % A
% Cys: 29 0 8 8 0 0 8 0 0 0 8 8 15 0 0 % C
% Asp: 0 8 0 0 8 0 8 8 15 36 15 29 0 65 0 % D
% Glu: 0 0 0 0 0 0 0 0 15 0 29 0 0 0 8 % E
% Phe: 0 8 15 0 8 0 8 0 0 0 0 0 0 0 29 % F
% Gly: 29 8 0 8 8 36 0 0 8 0 8 8 0 8 8 % G
% His: 0 0 0 0 0 36 0 0 0 15 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 8 0 0 0 15 0 8 0 % I
% Lys: 8 0 0 0 0 0 0 0 0 8 0 8 0 8 8 % K
% Leu: 0 0 0 8 0 8 22 8 0 0 8 15 15 8 0 % L
% Met: 0 0 0 29 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 0 0 8 0 0 0 29 0 0 0 0 8 0 0 % N
% Pro: 0 0 29 0 0 0 8 0 0 0 8 0 8 0 8 % P
% Gln: 8 0 8 29 0 8 0 0 0 8 0 8 0 8 0 % Q
% Arg: 0 0 8 0 72 0 8 8 8 15 8 0 0 0 0 % R
% Ser: 0 36 8 8 0 8 0 22 36 8 0 15 43 0 0 % S
% Thr: 0 8 0 0 8 0 8 22 8 0 0 0 0 0 15 % T
% Val: 0 29 22 8 0 0 15 0 8 0 8 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 22 0 8 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _