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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOCS1 All Species: 27.88
Human Site: T587 Identified Species: 47.18
UniProt: Q9NZB8 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZB8 NP_001068566.1 636 70105 T587 S C R A R G P T G V E M E A L
Chimpanzee Pan troglodytes XP_001173932 638 70317 T589 S C R A R G P T G V E M E A L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_538905 634 69857 T585 S C R A W G P T G V E M E A L
Cat Felis silvestris
Mouse Mus musculus Q5RKZ7 636 69840 T587 S C R A R G P T G V E M E A L
Rat Rattus norvegicus NP_001100351 480 53567 P434 H S V P M A L P L S Q Q C L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506834 604 66014 T548 T C R A R G P T G V E M E A L
Chicken Gallus gallus XP_419475 724 79312 T658 S C Q T W G K T G V E M E A L
Frog Xenopus laevis NP_001086201 389 43733 R343 G N S E V S L R D C L R S E V
Zebra Danio Brachydanio rerio NP_001099130 402 45478 R356 G N A E V S L R D F L R S G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8IQF1 565 63239 A519 A L T A V S V A A L T V Y D M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q20624 600 67438 T547 T A R C S G N T G V E M E A L
Sea Urchin Strong. purpuratus XP_783948 669 74015 T618 K V K C I G R T G V E M E A L
Poplar Tree Populus trichocarpa XP_002314219 355 40047 R309 G P S E V S L R D P L R E G A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39055 390 43395 R344 G P S E V S L R D P L R S G A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.1 N.A. 86.4 N.A. 84.9 62.1 N.A. 66.1 61.7 45.9 42.1 N.A. 47.9 N.A. 41.3 50.8
Protein Similarity: 100 98.1 N.A. 92.9 N.A. 91.3 68 N.A. 77 72.5 52.8 51.2 N.A. 63.8 N.A. 57.8 66.6
P-Site Identity: 100 100 N.A. 93.3 N.A. 100 0 N.A. 93.3 73.3 0 0 N.A. 6.6 N.A. 66.6 60
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 6.6 N.A. 100 80 6.6 0 N.A. 33.3 N.A. 73.3 66.6
Percent
Protein Identity: 35.2 N.A. N.A. 34.5 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 44 N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 43 0 8 0 8 8 0 0 0 0 58 22 % A
% Cys: 0 43 0 15 0 0 0 0 0 8 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 29 0 0 0 0 8 0 % D
% Glu: 0 0 0 29 0 0 0 0 0 0 58 0 65 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 29 0 0 0 0 58 0 0 58 0 0 0 0 22 8 % G
% His: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 0 8 0 0 0 0 36 0 8 8 29 0 0 8 58 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 58 0 0 8 % M
% Asn: 0 15 0 0 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 0 15 0 8 0 0 36 8 0 15 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 8 8 0 0 0 % Q
% Arg: 0 0 43 0 29 0 8 29 0 0 0 29 0 0 0 % R
% Ser: 36 8 22 0 8 36 0 0 0 8 0 0 22 0 0 % S
% Thr: 15 0 8 8 0 0 0 58 0 0 8 0 0 0 0 % T
% Val: 0 8 8 0 36 0 8 0 0 58 0 8 0 0 8 % V
% Trp: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _