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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WWOX All Species: 9.7
Human Site: Y107 Identified Species: 16.41
UniProt: Q9NZC7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZC7 NP_057457.1 414 46677 Y107 K P T T R Q R Y D G S T T A M
Chimpanzee Pan troglodytes XP_001144696 363 41022 N70 W E Q E T D E N G Q V F F V D
Rhesus Macaque Macaca mulatta XP_001105944 398 45056 Q105 P T K P S T Q Q R Y D G S T T
Dog Lupus familis XP_852623 383 43043 L90 T T Y L D P R L A F T V D D N
Cat Felis silvestris
Mouse Mus musculus Q91WL8 414 46494 Y107 K P T T R Q R Y D G S T T A M
Rat Rattus norvegicus NP_001099658 356 40173 W63 A G D L P Y G W E Q E T D E N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505354 146 16628
Chicken Gallus gallus Q5F389 414 46711 Y107 K P P T R Q K Y D G N S T A M
Frog Xenopus laevis NP_001088080 143 16305
Zebra Danio Brachydanio rerio Q803A8 412 46303 N107 K P K R Y D G N T G A L E I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 A110 R F D S C S T A L Q V L H G K
Honey Bee Apis mellifera XP_395282 414 46992 S106 M R Q R F D G S S T A L S V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789399 410 45991 A107 K L A Q R F D A Y S T A L H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 L106 G A S S G L G L A T A K A L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.5 84.7 82.8 N.A. 93.7 81.1 N.A. 26 83 29.2 71.9 N.A. 48.3 51.2 N.A. 56.2
Protein Similarity: 100 86.2 88.4 87.4 N.A. 96.1 83.8 N.A. 29.4 93 33.3 84.3 N.A. 65.2 66.6 N.A. 73.4
P-Site Identity: 100 0 0 6.6 N.A. 100 6.6 N.A. 0 73.3 0 20 N.A. 0 0 N.A. 13.3
P-Site Similarity: 100 0 13.3 13.3 N.A. 100 20 N.A. 0 93.3 0 33.3 N.A. 13.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 28.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 0 0 0 15 15 0 22 8 8 22 8 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 15 0 8 22 8 0 22 0 8 0 15 8 8 % D
% Glu: 0 8 0 8 0 0 8 0 8 0 8 0 8 8 0 % E
% Phe: 0 8 0 0 8 8 0 0 0 8 0 8 8 0 0 % F
% Gly: 8 8 0 0 8 0 29 0 8 29 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % I
% Lys: 36 0 15 0 0 0 8 0 0 0 0 8 0 0 8 % K
% Leu: 0 8 0 15 0 8 0 15 8 0 0 22 8 8 15 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 22 % M
% Asn: 0 0 0 0 0 0 0 15 0 0 8 0 0 0 15 % N
% Pro: 8 29 8 8 8 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 15 8 0 22 8 8 0 22 0 0 0 0 0 % Q
% Arg: 8 8 0 15 29 0 22 0 8 0 0 0 0 0 0 % R
% Ser: 0 0 8 15 8 8 0 8 8 8 15 8 15 0 0 % S
% Thr: 8 15 15 22 8 8 8 0 8 15 15 22 22 8 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 15 8 0 15 8 % V
% Trp: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 8 8 0 22 8 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _