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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WWOX All Species: 17.58
Human Site: Y287 Identified Species: 29.74
UniProt: Q9NZC7 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZC7 NP_057457.1 414 46677 Y287 L S P T K N D Y W A M L A Y N
Chimpanzee Pan troglodytes XP_001144696 363 41022 F237 Q V N H L G H F Y L V Q L L Q
Rhesus Macaque Macaca mulatta XP_001105944 398 45056 L272 F T D I N D S L G K L D F S R
Dog Lupus familis XP_852623 383 43043 V257 S A P A R V V V V S S E S H R
Cat Felis silvestris
Mouse Mus musculus Q91WL8 414 46494 Y287 L S P P R S D Y W A M L A Y N
Rat Rattus norvegicus NP_001099658 356 40173 Q230 D G L E T T F Q V N H L G H F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505354 146 16628 T19 F I A A L T P T G R L R A E R
Chicken Gallus gallus Q5F389 414 46711 Y287 L S P S K K E Y W A M L A Y N
Frog Xenopus laevis NP_001088080 143 16305 E17 D D T D S E D E L P P G W E E
Zebra Danio Brachydanio rerio Q803A8 412 46303 Y284 L S P P Q K N Y W S L L A Y N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VLU5 409 46492 Y282 L S P P P E K Y W S M M A Y N
Honey Bee Apis mellifera XP_395282 414 46992 Y280 L S L S P P A Y K Y W F M G A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789399 410 45991 F283 V A M P K D K F W P I L A Y G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42536 405 43844 V275 M I D G G D F V G A K A Y K D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.5 84.7 82.8 N.A. 93.7 81.1 N.A. 26 83 29.2 71.9 N.A. 48.3 51.2 N.A. 56.2
Protein Similarity: 100 86.2 88.4 87.4 N.A. 96.1 83.8 N.A. 29.4 93 33.3 84.3 N.A. 65.2 66.6 N.A. 73.4
P-Site Identity: 100 0 0 6.6 N.A. 80 6.6 N.A. 6.6 80 6.6 60 N.A. 60 20 N.A. 33.3
P-Site Similarity: 100 20 20 40 N.A. 93.3 13.3 N.A. 13.3 93.3 6.6 86.6 N.A. 73.3 26.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. 28.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 44.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 8 15 0 0 8 0 0 29 0 8 50 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 8 15 8 0 22 22 0 0 0 0 8 0 0 8 % D
% Glu: 0 0 0 8 0 15 8 8 0 0 0 8 0 15 8 % E
% Phe: 15 0 0 0 0 0 15 15 0 0 0 8 8 0 8 % F
% Gly: 0 8 0 8 8 8 0 0 22 0 0 8 8 8 8 % G
% His: 0 0 0 8 0 0 8 0 0 0 8 0 0 15 0 % H
% Ile: 0 15 0 8 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 0 0 0 22 15 15 0 8 8 8 0 0 8 0 % K
% Leu: 43 0 15 0 15 0 0 8 8 8 22 43 8 8 0 % L
% Met: 8 0 8 0 0 0 0 0 0 0 29 8 8 0 0 % M
% Asn: 0 0 8 0 8 8 8 0 0 8 0 0 0 0 36 % N
% Pro: 0 0 43 29 15 8 8 0 0 15 8 0 0 0 0 % P
% Gln: 8 0 0 0 8 0 0 8 0 0 0 8 0 0 8 % Q
% Arg: 0 0 0 0 15 0 0 0 0 8 0 8 0 0 22 % R
% Ser: 8 43 0 15 8 8 8 0 0 22 8 0 8 8 0 % S
% Thr: 0 8 8 8 8 15 0 8 0 0 0 0 0 0 0 % T
% Val: 8 8 0 0 0 8 8 15 15 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 43 0 8 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 43 8 8 0 0 8 43 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _