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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPG21
All Species:
39.39
Human Site:
S125
Identified Species:
61.9
UniProt:
Q9NZD8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZD8
NP_001121361.1
308
34960
S125
F
A
E
Y
T
H
K
S
P
R
V
H
S
L
I
Chimpanzee
Pan troglodytes
XP_510477
374
41733
S191
F
A
E
Y
T
H
K
S
P
R
V
H
S
L
I
Rhesus Macaque
Macaca mulatta
XP_001101919
510
57163
S327
F
A
E
Y
T
H
K
S
P
R
V
H
S
L
I
Dog
Lupus familis
XP_852491
308
35045
S125
F
A
E
Y
T
H
K
S
P
R
V
H
S
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQC8
308
34934
S125
F
A
E
Y
T
H
K
S
P
R
V
H
S
L
I
Rat
Rattus norvegicus
Q5XIC4
261
29557
F87
V
Y
W
D
H
L
E
F
C
D
G
F
R
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515770
309
35053
S125
F
A
E
Y
T
H
K
S
P
R
V
H
S
L
I
Chicken
Gallus gallus
XP_413895
310
35255
S125
F
A
E
Y
T
H
K
S
P
R
V
Q
S
L
I
Frog
Xenopus laevis
Q5FVD6
310
35267
S125
F
A
E
Y
T
H
K
S
P
R
V
Q
S
L
I
Zebra Danio
Brachydanio rerio
Q6PC62
311
35552
S125
F
A
E
V
T
Y
K
S
P
R
V
H
S
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392210
292
32931
L117
G
A
S
L
G
G
F
L
A
Q
K
F
T
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782145
402
45740
S126
F
A
E
Y
T
F
R
S
P
R
V
A
S
L
I
Poplar Tree
Populus trichocarpa
XP_002329856
418
47206
R122
F
A
Q
H
R
P
R
R
V
R
S
L
I
L
S
Maize
Zea mays
NP_001150628
354
39212
R125
F
A
E
H
R
P
R
R
V
K
S
L
V
L
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192960
392
43529
R122
F
A
H
H
R
P
R
R
V
K
S
L
V
L
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.1
58.8
98.6
N.A.
97.7
81.8
N.A.
96.7
95.1
88.7
87.1
N.A.
N.A.
58.1
N.A.
47.5
Protein Similarity:
100
80.4
60
99.3
N.A.
99
83.4
N.A.
98
97
93.2
93.8
N.A.
N.A.
75.3
N.A.
62.9
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
100
93.3
93.3
80
N.A.
N.A.
6.6
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
100
93.3
93.3
93.3
N.A.
N.A.
26.6
N.A.
86.6
Percent
Protein Identity:
33.2
37.2
N.A.
34.6
N.A.
N.A.
Protein Similarity:
48.3
55.6
N.A.
51.2
N.A.
N.A.
P-Site Identity:
26.6
26.6
N.A.
20
N.A.
N.A.
P-Site Similarity:
46.6
46.6
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
94
0
0
0
0
0
0
7
0
0
7
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
74
0
0
0
7
0
0
0
0
0
0
7
0
% E
% Phe:
87
0
0
0
0
7
7
7
0
0
0
14
0
0
0
% F
% Gly:
7
0
0
0
7
7
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
7
20
7
54
0
0
0
0
0
47
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
60
% I
% Lys:
0
0
0
0
0
0
60
0
0
14
7
0
0
7
0
% K
% Leu:
0
0
0
7
0
7
0
7
0
0
0
20
0
87
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
20
0
0
67
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
0
0
0
0
7
0
14
0
0
0
% Q
% Arg:
0
0
0
0
20
0
27
20
0
74
0
0
7
0
0
% R
% Ser:
0
0
7
0
0
0
0
67
0
0
20
0
67
0
20
% S
% Thr:
0
0
0
0
67
0
0
0
0
0
0
0
7
0
0
% T
% Val:
7
0
0
7
0
0
0
0
20
0
67
0
14
0
14
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
0
60
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _