KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPG21
All Species:
19.09
Human Site:
S300
Identified Species:
30
UniProt:
Q9NZD8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZD8
NP_001121361.1
308
34960
S300
E
L
E
V
Q
K
G
S
L
G
I
S
Q
E
E
Chimpanzee
Pan troglodytes
XP_510477
374
41733
S366
E
L
E
V
Q
K
G
S
L
G
I
S
Q
E
E
Rhesus Macaque
Macaca mulatta
XP_001101919
510
57163
S502
E
L
E
V
Q
K
G
S
L
G
I
N
Q
E
E
Dog
Lupus familis
XP_852491
308
35045
S300
E
L
E
V
Q
K
G
S
L
S
I
S
Q
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQC8
308
34934
R300
E
L
E
V
Q
K
G
R
L
G
L
S
Q
E
E
Rat
Rattus norvegicus
Q5XIC4
261
29557
L254
L
D
V
Q
K
G
Q
L
D
L
S
Q
E
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515770
309
35053
K300
E
L
E
V
Q
K
G
K
L
C
I
S
E
Q
E
Chicken
Gallus gallus
XP_413895
310
35255
S300
E
L
E
V
Q
K
I
S
L
H
T
S
S
E
Q
Frog
Xenopus laevis
Q5FVD6
310
35267
F300
E
L
E
V
Q
K
S
F
P
Q
T
T
V
E
A
Zebra Danio
Brachydanio rerio
Q6PC62
311
35552
H300
E
L
E
V
Q
R
T
H
L
S
N
N
S
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392210
292
32931
Y284
R
Q
F
E
G
T
E
Y
A
A
S
E
R
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782145
402
45740
A384
P
E
L
A
T
E
A
A
S
T
S
Q
N
G
T
Poplar Tree
Populus trichocarpa
XP_002329856
418
47206
S296
T
G
G
S
Y
S
E
S
E
D
G
K
G
D
R
Maize
Zea mays
NP_001150628
354
39212
Q299
S
A
G
S
S
K
D
Q
K
D
G
G
D
S
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192960
392
43529
S296
A
D
G
T
D
G
S
S
Q
S
K
K
K
S
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.1
58.8
98.6
N.A.
97.7
81.8
N.A.
96.7
95.1
88.7
87.1
N.A.
N.A.
58.1
N.A.
47.5
Protein Similarity:
100
80.4
60
99.3
N.A.
99
83.4
N.A.
98
97
93.2
93.8
N.A.
N.A.
75.3
N.A.
62.9
P-Site Identity:
100
100
93.3
93.3
N.A.
86.6
6.6
N.A.
73.3
66.6
46.6
46.6
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
20
N.A.
86.6
73.3
53.3
60
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
33.2
37.2
N.A.
34.6
N.A.
N.A.
Protein Similarity:
48.3
55.6
N.A.
51.2
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
13.3
6.6
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
7
0
0
7
7
7
7
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
14
0
0
7
0
7
0
7
14
0
0
7
7
7
% D
% Glu:
60
7
60
7
0
7
14
0
7
0
0
7
14
60
40
% E
% Phe:
0
0
7
0
0
0
0
7
0
0
0
0
0
0
7
% F
% Gly:
0
7
20
0
7
14
40
0
0
27
14
7
7
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
7
0
0
0
34
0
0
0
0
% I
% Lys:
0
0
0
0
7
60
0
7
7
0
7
14
7
7
7
% K
% Leu:
7
60
7
0
0
0
0
7
54
7
7
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
7
14
7
0
0
% N
% Pro:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% P
% Gln:
0
7
0
7
60
0
7
7
7
7
0
14
34
7
7
% Q
% Arg:
7
0
0
0
0
7
0
7
0
0
0
0
7
0
7
% R
% Ser:
7
0
0
14
7
7
14
47
7
20
20
40
14
14
7
% S
% Thr:
7
0
0
7
7
7
7
0
0
7
14
7
0
0
7
% T
% Val:
0
0
7
60
0
0
0
0
0
0
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _