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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPG21 All Species: 20.22
Human Site: S304 Identified Species: 31.77
UniProt: Q9NZD8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZD8 NP_001121361.1 308 34960 S304 Q K G S L G I S Q E E Q _ _ _
Chimpanzee Pan troglodytes XP_510477 374 41733 S370 Q K G S L G I S Q E E Q _ _ _
Rhesus Macaque Macaca mulatta XP_001101919 510 57163 N506 Q K G S L G I N Q E E Q _ _ _
Dog Lupus familis XP_852491 308 35045 S304 Q K G S L S I S Q E E Q _ _ _
Cat Felis silvestris
Mouse Mus musculus Q9CQC8 308 34934 S304 Q K G R L G L S Q E E P _ _ _
Rat Rattus norvegicus Q5XIC4 261 29557
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515770 309 35053 S304 Q K G K L C I S E Q E E Q _ _
Chicken Gallus gallus XP_413895 310 35255 S304 Q K I S L H T S S E Q E E Q _
Frog Xenopus laevis Q5FVD6 310 35267 T304 Q K S F P Q T T V E A E E S _
Zebra Danio Brachydanio rerio Q6PC62 311 35552 N304 Q R T H L S N N S E S E D E S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392210 292 32931 E288 G T E Y A A S E R K K L _ _ _
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782145 402 45740 Q388 T E A A S T S Q N G T G T S E
Poplar Tree Populus trichocarpa XP_002329856 418 47206 K300 Y S E S E D G K G D R D D Q P
Maize Zea mays NP_001150628 354 39212 G303 S K D Q K D G G D S F D N S G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_192960 392 43529 K300 D G S S Q S K K K S D E E K D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.1 58.8 98.6 N.A. 97.7 81.8 N.A. 96.7 95.1 88.7 87.1 N.A. N.A. 58.1 N.A. 47.5
Protein Similarity: 100 80.4 60 99.3 N.A. 99 83.4 N.A. 98 97 93.2 93.8 N.A. N.A. 75.3 N.A. 62.9
P-Site Identity: 100 100 91.6 91.6 N.A. 75 0 N.A. 53.8 42.8 21.4 20 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 91.6 N.A. 83.3 0 N.A. 76.9 57.1 35.7 40 N.A. N.A. 25 N.A. 13.3
Percent
Protein Identity: 33.2 37.2 N.A. 34.6 N.A. N.A.
Protein Similarity: 48.3 55.6 N.A. 51.2 N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. 6.6 N.A. N.A.
P-Site Similarity: 13.3 13.3 N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 7 7 0 0 0 0 7 0 0 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 14 0 0 7 7 7 14 14 0 7 % D
% Glu: 0 7 14 0 7 0 0 7 7 54 40 34 20 7 7 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % F
% Gly: 7 7 40 0 0 27 14 7 7 7 0 7 0 0 7 % G
% His: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 7 0 0 0 34 0 0 0 0 0 0 0 0 % I
% Lys: 0 60 0 7 7 0 7 14 7 7 7 0 0 7 0 % K
% Leu: 0 0 0 0 54 0 7 0 0 0 0 7 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 14 7 0 0 0 7 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 7 % P
% Gln: 60 0 0 7 7 7 0 7 34 7 7 27 7 14 0 % Q
% Arg: 0 7 0 7 0 0 0 0 7 0 7 0 0 0 0 % R
% Ser: 7 7 14 47 7 20 14 40 14 14 7 0 0 20 7 % S
% Thr: 7 7 7 0 0 7 14 7 0 0 7 0 7 0 0 % T
% Val: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 40 47 60 % _