KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPG21
All Species:
37.58
Human Site:
Y281
Identified Species:
59.05
UniProt:
Q9NZD8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZD8
NP_001121361.1
308
34960
Y281
L
Q
F
H
G
T
K
Y
A
A
I
D
P
S
M
Chimpanzee
Pan troglodytes
XP_510477
374
41733
Y347
L
Q
F
H
G
T
K
Y
A
A
I
D
P
S
M
Rhesus Macaque
Macaca mulatta
XP_001101919
510
57163
Y483
L
Q
F
H
G
T
K
Y
A
A
I
D
P
S
M
Dog
Lupus familis
XP_852491
308
35045
Y281
L
Q
F
H
G
T
K
Y
A
A
I
D
P
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQC8
308
34934
Y281
L
Q
F
H
G
T
K
Y
A
A
I
D
P
S
V
Rat
Rattus norvegicus
Q5XIC4
261
29557
A235
Q
F
H
G
T
K
Y
A
A
I
D
P
S
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515770
309
35053
Y281
L
P
F
H
G
T
K
Y
A
A
I
D
P
S
M
Chicken
Gallus gallus
XP_413895
310
35255
Y281
L
Q
F
H
G
T
R
Y
A
A
I
D
P
S
M
Frog
Xenopus laevis
Q5FVD6
310
35267
Y281
R
Q
F
H
G
T
R
Y
A
A
I
D
P
A
M
Zebra Danio
Brachydanio rerio
Q6PC62
311
35552
Y281
R
Q
F
H
G
T
R
Y
A
A
I
S
P
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392210
292
32931
A265
N
F
P
Y
L
S
R
A
A
E
V
N
L
H
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782145
402
45740
Y365
R
R
F
L
D
G
R
Y
S
A
R
D
H
A
I
Poplar Tree
Populus trichocarpa
XP_002329856
418
47206
R277
R
R
V
G
V
E
A
R
P
D
L
V
R
G
I
Maize
Zea mays
NP_001150628
354
39212
R280
R
R
V
G
V
E
P
R
S
D
L
V
Q
G
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192960
392
43529
R277
R
R
V
G
V
E
P
R
P
E
V
V
K
S
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.1
58.8
98.6
N.A.
97.7
81.8
N.A.
96.7
95.1
88.7
87.1
N.A.
N.A.
58.1
N.A.
47.5
Protein Similarity:
100
80.4
60
99.3
N.A.
99
83.4
N.A.
98
97
93.2
93.8
N.A.
N.A.
75.3
N.A.
62.9
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
93.3
93.3
80
73.3
N.A.
N.A.
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
93.3
100
93.3
80
N.A.
N.A.
46.6
N.A.
60
Percent
Protein Identity:
33.2
37.2
N.A.
34.6
N.A.
N.A.
Protein Similarity:
48.3
55.6
N.A.
51.2
N.A.
N.A.
P-Site Identity:
0
0
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
20
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
14
74
67
0
0
0
14
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
14
7
60
0
0
0
% D
% Glu:
0
0
0
0
0
20
0
0
0
14
0
0
0
7
0
% E
% Phe:
0
14
67
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
0
0
27
60
7
0
0
0
0
0
0
0
14
0
% G
% His:
0
0
7
60
0
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
7
60
0
0
0
20
% I
% Lys:
0
0
0
0
0
7
40
0
0
0
0
0
7
0
0
% K
% Leu:
47
0
0
7
7
0
0
0
0
0
14
0
7
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% M
% Asn:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% N
% Pro:
0
7
7
0
0
0
14
0
14
0
0
7
60
0
0
% P
% Gln:
7
54
0
0
0
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
40
27
0
0
0
0
34
20
0
0
7
0
7
0
0
% R
% Ser:
0
0
0
0
0
7
0
0
14
0
0
7
7
54
0
% S
% Thr:
0
0
0
0
7
60
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
20
0
20
0
0
0
0
0
14
20
0
7
14
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
7
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _