KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTTG2
All Species:
12.73
Human Site:
T66
Identified Species:
31.11
UniProt:
Q9NZH5
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZH5
NP_006598.2
202
22243
T66
A
T
R
K
A
L
G
T
V
N
R
A
T
E
K
Chimpanzee
Pan troglodytes
A2T767
202
21981
T66
A
T
R
K
A
L
G
T
V
N
R
A
T
E
K
Rhesus Macaque
Macaca mulatta
XP_001085022
202
22035
T66
A
T
R
K
A
L
G
T
V
N
R
A
T
E
K
Dog
Lupus familis
XP_536445
201
21988
T66
V
A
R
K
A
L
G
T
V
N
R
A
T
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQJ7
199
21707
R66
K
A
L
G
T
V
N
R
V
A
E
K
P
M
K
Rat
Rattus norvegicus
P97613
199
21552
R66
K
A
L
G
T
V
N
R
V
T
E
K
P
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505936
201
22331
N66
S
V
R
K
V
L
G
N
V
N
R
T
L
E
T
Chicken
Gallus gallus
XP_001232400
203
22717
G70
C
S
V
R
K
A
L
G
N
V
N
R
T
V
G
Frog
Xenopus laevis
NP_001081983
188
20636
N60
P
S
R
K
A
L
G
N
V
N
K
Q
I
L
P
Zebra Danio
Brachydanio rerio
XP_695066
182
20460
A54
P
L
Q
S
S
R
K
A
L
G
V
I
N
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
91.5
79.6
N.A.
67.3
66.3
N.A.
53.9
41.3
33.1
30.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
91.5
92.5
86.1
N.A.
77.7
77.2
N.A.
68.8
56.6
50.5
50.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
13.3
13.3
N.A.
53.3
6.6
46.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
20
20
N.A.
60
20
60
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
30
0
0
50
10
0
10
0
10
0
40
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
20
0
0
50
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
20
0
0
60
10
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% I
% Lys:
20
0
0
60
10
0
10
0
0
0
10
20
0
10
50
% K
% Leu:
0
10
20
0
0
60
10
0
10
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
20
20
10
60
10
0
10
0
10
% N
% Pro:
20
0
0
0
0
0
0
0
0
0
0
0
20
0
10
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
60
10
0
10
0
20
0
0
50
10
0
0
0
% R
% Ser:
10
20
0
10
10
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
30
0
0
20
0
0
40
0
10
0
10
50
0
10
% T
% Val:
10
10
10
0
10
20
0
0
80
10
10
0
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _