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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTTG2 All Species: 13.64
Human Site: T77 Identified Species: 33.33
UniProt: Q9NZH5 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZH5 NP_006598.2 202 22243 T77 A T E K S V K T N G P R K Q K
Chimpanzee Pan troglodytes A2T767 202 21981 T77 A T E K S V K T K G P L K Q K
Rhesus Macaque Macaca mulatta XP_001085022 202 22035 T77 A T E K S V K T K G P L K Q K
Dog Lupus familis XP_536445 201 21988 T77 A T E N S V K T N G P L K Q K
Cat Felis silvestris
Mouse Mus musculus Q9CQJ7 199 21707 P77 K P M K T G K P L Q P K Q P T
Rat Rattus norvegicus P97613 199 21552 P77 K P V K S S K P L Q S K Q P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505936 201 22331 K77 T L E T A R K K N E P I K Q K
Chicken Gallus gallus XP_001232400 203 22717 K81 R T V G V T S K K E Q M R D K
Frog Xenopus laevis NP_001081983 188 20636 A71 Q I L P K T A A T A Q K S D L
Zebra Danio Brachydanio rerio XP_695066 182 20460 T65 I N K I V N Q T S S H E A E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 91.5 79.6 N.A. 67.3 66.3 N.A. 53.9 41.3 33.1 30.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 91.5 92.5 86.1 N.A. 77.7 77.2 N.A. 68.8 56.6 50.5 50.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 86.6 86.6 86.6 N.A. 20 20 N.A. 46.6 13.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 86.6 86.6 86.6 N.A. 40 33.3 N.A. 53.3 20 6.6 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 0 0 0 10 0 10 10 0 10 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % D
% Glu: 0 0 50 0 0 0 0 0 0 20 0 10 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 10 0 10 0 0 0 40 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 10 10 0 10 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 20 0 10 50 10 0 70 20 30 0 0 30 50 0 60 % K
% Leu: 0 10 10 0 0 0 0 0 20 0 0 30 0 0 10 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 10 0 10 0 10 0 0 30 0 0 0 0 0 0 % N
% Pro: 0 20 0 10 0 0 0 20 0 0 60 0 0 20 0 % P
% Gln: 10 0 0 0 0 0 10 0 0 20 20 0 20 50 0 % Q
% Arg: 10 0 0 0 0 10 0 0 0 0 0 10 10 0 0 % R
% Ser: 0 0 0 0 50 10 10 0 10 10 10 0 10 0 0 % S
% Thr: 10 50 0 10 10 20 0 50 10 0 0 0 0 0 20 % T
% Val: 0 0 20 0 20 40 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _