KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTL
All Species:
17.88
Human Site:
S441
Identified Species:
35.76
UniProt:
Q9NZJ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZJ0
NP_057532.2
730
79441
S441
P
R
A
K
C
N
P
S
N
S
S
P
S
S
A
Chimpanzee
Pan troglodytes
XP_525058
384
42363
E110
D
L
A
W
V
P
G
E
L
K
L
V
T
A
A
Rhesus Macaque
Macaca mulatta
XP_001108416
730
79487
S441
P
R
V
K
C
N
A
S
I
S
S
P
S
S
A
Dog
Lupus familis
XP_547399
730
79407
S441
P
R
V
K
S
S
P
S
I
S
S
P
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3TLR7
729
79113
S440
P
R
A
K
S
S
P
S
I
S
S
P
S
S
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509630
734
80183
S442
P
R
V
E
S
S
P
S
V
S
S
P
R
S
A
Chicken
Gallus gallus
Q5ZJW8
720
78614
C438
A
F
S
V
G
S
P
C
A
S
S
P
R
P
A
Frog
Xenopus laevis
NP_001090030
710
78256
S436
K
P
S
V
M
S
S
S
S
L
T
S
S
P
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24371
769
84099
T480
L
G
V
A
G
Q
E
T
E
A
T
E
Q
P
Q
Honey Bee
Apis mellifera
XP_395929
653
73736
S378
I
V
T
C
S
D
D
S
C
H
R
I
W
R
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789660
791
86742
P463
T
S
E
S
P
L
S
P
Q
P
S
P
T
P
S
Poplar Tree
Populus trichocarpa
XP_002300052
503
55905
A229
D
E
V
S
I
A
T
A
G
A
A
D
S
I
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.3
98.2
93.1
N.A.
89.5
N.A.
N.A.
70.3
60.5
57.2
N.A.
N.A.
27.9
30.1
N.A.
31.3
Protein Similarity:
100
52.5
98.6
95.3
N.A.
94.5
N.A.
N.A.
80.6
71.6
70.2
N.A.
N.A.
44.9
49.1
N.A.
47.6
P-Site Identity:
100
13.3
80
73.3
N.A.
80
N.A.
N.A.
60
33.3
13.3
N.A.
N.A.
0
6.6
N.A.
13.3
P-Site Similarity:
100
26.6
80
80
N.A.
86.6
N.A.
N.A.
73.3
46.6
40
N.A.
N.A.
20
13.3
N.A.
26.6
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
25
9
0
9
9
9
9
17
9
0
0
9
59
% A
% Cys:
0
0
0
9
17
0
0
9
9
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% D
% Glu:
0
9
9
9
0
0
9
9
9
0
0
9
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
17
0
9
0
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
0
0
9
0
0
0
25
0
0
9
0
9
9
% I
% Lys:
9
0
0
34
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
9
9
0
0
0
9
0
0
9
9
9
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
9
0
0
0
0
0
0
% N
% Pro:
42
9
0
0
9
9
42
9
0
9
0
59
0
34
0
% P
% Gln:
0
0
0
0
0
9
0
0
9
0
0
0
9
0
9
% Q
% Arg:
0
42
0
0
0
0
0
0
0
0
9
0
17
9
0
% R
% Ser:
0
9
17
17
34
42
17
59
9
50
59
9
50
42
9
% S
% Thr:
9
0
9
0
0
0
9
9
0
0
17
0
17
0
9
% T
% Val:
0
9
42
17
9
0
0
0
9
0
0
9
0
0
9
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _