Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTL All Species: 18.48
Human Site: S495 Identified Species: 36.97
UniProt: Q9NZJ0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZJ0 NP_057532.2 730 79441 S495 S V S P K P P S S F K M S I R
Chimpanzee Pan troglodytes XP_525058 384 42363 N164 C T G G R D G N I M V W D T R
Rhesus Macaque Macaca mulatta XP_001108416 730 79487 S495 S V S P K P P S S F K M S I R
Dog Lupus familis XP_547399 730 79407 S495 S V S P K P P S S F K M S I R
Cat Felis silvestris
Mouse Mus musculus Q3TLR7 729 79113 S494 S V S P K P L S S F K M S L R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509630 734 80183 S496 T S S P K P P S S S K M S I R
Chicken Gallus gallus Q5ZJW8 720 78614 P492 R T S P K L V P S S K M S I K
Frog Xenopus laevis NP_001090030 710 78256 M490 L G V S P K Q M S S S K M S I
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24371 769 84099 A534 K R Q K E N S A A E D V S P L
Honey Bee Apis mellifera XP_395929 653 73736 Y432 H C I I S E E Y T P G S D T I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789660 791 86742 G517 G Q A S Q P D G E S E S V L K
Poplar Tree Populus trichocarpa XP_002300052 503 55905 T283 N G V F L T A T C M D N R I Y
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.3 98.2 93.1 N.A. 89.5 N.A. N.A. 70.3 60.5 57.2 N.A. N.A. 27.9 30.1 N.A. 31.3
Protein Similarity: 100 52.5 98.6 95.3 N.A. 94.5 N.A. N.A. 80.6 71.6 70.2 N.A. N.A. 44.9 49.1 N.A. 47.6
P-Site Identity: 100 6.6 100 100 N.A. 86.6 N.A. N.A. 80 53.3 6.6 N.A. N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 20 100 100 N.A. 93.3 N.A. N.A. 86.6 60 6.6 N.A. N.A. 33.3 6.6 N.A. 40
Percent
Protein Identity: 25.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 38.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 20 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 0 9 9 9 0 0 0 0 0 0 % A
% Cys: 9 9 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 9 0 0 0 17 0 17 0 0 % D
% Glu: 0 0 0 0 9 9 9 0 9 9 9 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 34 0 0 0 0 0 % F
% Gly: 9 17 9 9 0 0 9 9 0 0 9 0 0 0 0 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 0 0 0 9 0 0 0 0 50 17 % I
% Lys: 9 0 0 9 50 9 0 0 0 0 50 9 0 0 17 % K
% Leu: 9 0 0 0 9 9 9 0 0 0 0 0 0 17 9 % L
% Met: 0 0 0 0 0 0 0 9 0 17 0 50 9 0 0 % M
% Asn: 9 0 0 0 0 9 0 9 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 50 9 50 34 9 0 9 0 0 0 9 0 % P
% Gln: 0 9 9 0 9 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 9 9 0 0 9 0 0 0 0 0 0 0 9 0 50 % R
% Ser: 34 9 50 17 9 0 9 42 59 34 9 17 59 9 0 % S
% Thr: 9 17 0 0 0 9 0 9 9 0 0 0 0 17 0 % T
% Val: 0 34 17 0 0 0 9 0 0 0 9 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _