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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTL
All Species:
19.7
Human Site:
S558
Identified Species:
39.39
UniProt:
Q9NZJ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZJ0
NP_057532.2
730
79441
S558
V
K
R
R
L
D
S
S
C
L
E
S
V
K
Q
Chimpanzee
Pan troglodytes
XP_525058
384
42363
E227
T
V
V
L
F
Q
D
E
N
T
L
V
S
A
G
Rhesus Macaque
Macaca mulatta
XP_001108416
730
79487
S558
V
K
R
R
L
D
S
S
C
L
E
S
V
K
Q
Dog
Lupus familis
XP_547399
730
79407
S558
V
K
R
R
L
D
S
S
C
L
E
S
V
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TLR7
729
79113
S557
V
K
R
R
L
D
S
S
C
L
E
S
V
K
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509630
734
80183
S559
A
K
R
R
L
D
S
S
C
P
D
S
I
E
P
Chicken
Gallus gallus
Q5ZJW8
720
78614
S555
A
K
R
R
L
D
C
S
K
E
D
E
A
G
Q
Frog
Xenopus laevis
NP_001090030
710
78256
E553
R
R
L
E
T
S
S
E
Y
A
E
H
V
C
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24371
769
84099
N597
S
P
T
S
N
L
P
N
Y
V
L
D
G
E
A
Honey Bee
Apis mellifera
XP_395929
653
73736
N495
I
L
S
P
I
E
E
N
L
T
S
I
T
K
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789660
791
86742
E580
Q
G
S
Q
A
N
E
E
T
E
F
A
L
K
R
Poplar Tree
Populus trichocarpa
XP_002300052
503
55905
D346
Q
V
N
K
P
D
V
D
P
I
T
L
K
T
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.3
98.2
93.1
N.A.
89.5
N.A.
N.A.
70.3
60.5
57.2
N.A.
N.A.
27.9
30.1
N.A.
31.3
Protein Similarity:
100
52.5
98.6
95.3
N.A.
94.5
N.A.
N.A.
80.6
71.6
70.2
N.A.
N.A.
44.9
49.1
N.A.
47.6
P-Site Identity:
100
0
100
100
N.A.
100
N.A.
N.A.
60
46.6
20
N.A.
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
0
100
100
N.A.
100
N.A.
N.A.
80
53.3
26.6
N.A.
N.A.
20
40
N.A.
40
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
0
0
9
0
0
0
0
9
0
9
9
9
9
% A
% Cys:
0
0
0
0
0
0
9
0
42
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
0
59
9
9
0
0
17
9
0
0
0
% D
% Glu:
0
0
0
9
0
9
17
25
0
17
42
9
0
17
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% H
% Ile:
9
0
0
0
9
0
0
0
0
9
0
9
9
0
0
% I
% Lys:
0
50
0
9
0
0
0
0
9
0
0
0
9
50
0
% K
% Leu:
0
9
9
9
50
9
0
0
9
34
17
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
9
0
17
9
0
0
0
0
0
0
% N
% Pro:
0
9
0
9
9
0
9
0
9
9
0
0
0
0
17
% P
% Gln:
17
0
0
9
0
9
0
0
0
0
0
0
0
0
42
% Q
% Arg:
9
9
50
50
0
0
0
0
0
0
0
0
0
0
17
% R
% Ser:
9
0
17
9
0
9
50
50
0
0
9
42
9
0
0
% S
% Thr:
9
0
9
0
9
0
0
0
9
17
9
0
9
9
0
% T
% Val:
34
17
9
0
0
0
9
0
0
9
0
9
42
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _