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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTL
All Species:
16.67
Human Site:
S656
Identified Species:
33.33
UniProt:
Q9NZJ0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZJ0
NP_057532.2
730
79441
S656
M
V
G
K
E
N
S
S
P
E
N
K
N
W
L
Chimpanzee
Pan troglodytes
XP_525058
384
42363
N316
A
I
F
N
G
H
Q
N
S
T
F
Y
V
K
S
Rhesus Macaque
Macaca mulatta
XP_001108416
730
79487
S656
M
V
G
K
E
N
S
S
P
E
N
K
N
W
L
Dog
Lupus familis
XP_547399
730
79407
S656
V
V
G
K
E
N
S
S
P
E
N
K
N
W
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TLR7
729
79113
S655
M
V
G
K
E
N
S
S
P
E
N
K
N
W
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509630
734
80183
S656
K
V
T
D
K
E
N
S
S
P
N
W
L
A
A
Chicken
Gallus gallus
Q5ZJW8
720
78614
D650
E
R
D
S
D
V
V
D
K
E
N
S
S
P
E
Frog
Xenopus laevis
NP_001090030
710
78256
N642
S
V
L
L
D
K
E
N
S
S
P
E
K
N
W
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24371
769
84099
G690
G
G
G
G
T
P
A
G
S
S
S
H
S
H
S
Honey Bee
Apis mellifera
XP_395929
653
73736
R584
E
N
V
D
W
L
T
R
I
R
R
E
K
Y
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789660
791
86742
T690
D
Q
P
E
T
T
L
T
S
I
Q
R
S
P
L
Poplar Tree
Populus trichocarpa
XP_002300052
503
55905
E435
D
N
L
L
P
S
D
E
V
F
N
Q
N
N
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.3
98.2
93.1
N.A.
89.5
N.A.
N.A.
70.3
60.5
57.2
N.A.
N.A.
27.9
30.1
N.A.
31.3
Protein Similarity:
100
52.5
98.6
95.3
N.A.
94.5
N.A.
N.A.
80.6
71.6
70.2
N.A.
N.A.
44.9
49.1
N.A.
47.6
P-Site Identity:
100
0
100
93.3
N.A.
100
N.A.
N.A.
20
13.3
6.6
N.A.
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
N.A.
N.A.
33.3
26.6
26.6
N.A.
N.A.
26.6
20
N.A.
33.3
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
0
0
0
0
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
17
17
0
9
9
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
9
34
9
9
9
0
42
0
17
0
0
17
% E
% Phe:
0
0
9
0
0
0
0
0
0
9
9
0
0
0
0
% F
% Gly:
9
9
42
9
9
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
9
0
9
0
% H
% Ile:
0
9
0
0
0
0
0
0
9
9
0
0
0
0
0
% I
% Lys:
9
0
0
34
9
9
0
0
9
0
0
34
17
9
0
% K
% Leu:
0
0
17
17
0
9
9
0
0
0
0
0
9
0
42
% L
% Met:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
0
9
0
34
9
17
0
0
59
0
42
17
0
% N
% Pro:
0
0
9
0
9
9
0
0
34
9
9
0
0
17
9
% P
% Gln:
0
9
0
0
0
0
9
0
0
0
9
9
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
9
0
9
9
9
0
0
0
% R
% Ser:
9
0
0
9
0
9
34
42
42
17
9
9
25
0
17
% S
% Thr:
0
0
9
0
17
9
9
9
0
9
0
0
0
0
0
% T
% Val:
9
50
9
0
0
9
9
0
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
9
0
34
9
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _