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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DTL
All Species:
0.91
Human Site:
T405
Identified Species:
1.82
UniProt:
Q9NZJ0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZJ0
NP_057532.2
730
79441
T405
P
G
G
D
K
L
S
T
V
G
W
A
S
Q
K
Chimpanzee
Pan troglodytes
XP_525058
384
42363
G74
L
A
V
A
N
E
E
G
F
V
R
L
Y
N
T
Rhesus Macaque
Macaca mulatta
XP_001108416
730
79487
M405
P
G
S
D
K
F
S
M
V
G
W
A
S
Q
K
Dog
Lupus familis
XP_547399
730
79407
I405
S
G
G
D
K
L
S
I
V
G
W
A
S
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3TLR7
729
79113
I404
K
P
G
D
K
H
S
I
V
G
W
T
S
Q
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509630
734
80183
L406
L
T
P
G
K
M
A
L
V
G
W
A
Y
Q
K
Chicken
Gallus gallus
Q5ZJW8
720
78614
K402
K
S
V
S
N
K
A
K
L
V
G
W
V
T
Q
Frog
Xenopus laevis
NP_001090030
710
78256
E400
R
S
C
E
D
S
S
E
S
D
K
R
D
S
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24371
769
84099
R444
R
D
L
E
S
T
P
R
S
L
K
R
L
M
D
Honey Bee
Apis mellifera
XP_395929
653
73736
S342
L
A
Y
I
W
H
T
S
K
P
G
A
P
V
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789660
791
86742
K427
G
R
A
R
R
C
E
K
K
P
V
T
E
S
Q
Poplar Tree
Populus trichocarpa
XP_002300052
503
55905
Q193
V
A
P
A
A
M
V
Q
G
A
H
L
S
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.3
98.2
93.1
N.A.
89.5
N.A.
N.A.
70.3
60.5
57.2
N.A.
N.A.
27.9
30.1
N.A.
31.3
Protein Similarity:
100
52.5
98.6
95.3
N.A.
94.5
N.A.
N.A.
80.6
71.6
70.2
N.A.
N.A.
44.9
49.1
N.A.
47.6
P-Site Identity:
100
0
80
86.6
N.A.
66.6
N.A.
N.A.
46.6
0
6.6
N.A.
N.A.
0
6.6
N.A.
0
P-Site Similarity:
100
0
80
86.6
N.A.
66.6
N.A.
N.A.
60
20
13.3
N.A.
N.A.
6.6
20
N.A.
13.3
Percent
Protein Identity:
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
38.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
9
17
9
0
17
0
0
9
0
42
0
0
0
% A
% Cys:
0
0
9
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
34
9
0
0
0
0
9
0
0
9
0
9
% D
% Glu:
0
0
0
17
0
9
17
9
0
0
0
0
9
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% F
% Gly:
9
25
25
9
0
0
0
9
9
42
17
0
0
0
0
% G
% His:
0
0
0
0
0
17
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
17
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
0
42
9
0
17
17
0
17
0
0
0
42
% K
% Leu:
25
0
9
0
0
17
0
9
9
9
0
17
9
0
0
% L
% Met:
0
0
0
0
0
17
0
9
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
17
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
17
9
17
0
0
0
9
0
0
17
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
9
0
0
0
0
0
42
17
% Q
% Arg:
17
9
0
9
9
0
0
9
0
0
9
17
0
0
9
% R
% Ser:
9
17
9
9
9
9
42
9
17
0
0
0
42
25
0
% S
% Thr:
0
9
0
0
0
9
9
9
0
0
0
17
0
9
9
% T
% Val:
9
0
17
0
0
0
9
0
42
17
9
0
9
9
17
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
42
9
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
17
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _