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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ITSN2
All Species:
19.09
Human Site:
S221
Identified Species:
52.5
UniProt:
Q9NZM3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZM3
NP_006268.2
1697
193461
S221
L
G
S
S
S
S
T
S
S
T
A
S
L
S
G
Chimpanzee
Pan troglodytes
XP_515329
1656
188783
S220
L
G
S
S
S
S
T
S
S
T
A
S
L
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_849291
1695
193027
S221
L
G
S
S
S
S
T
S
S
T
A
S
L
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0R6
1659
188889
S222
L
G
S
S
S
S
T
S
S
T
A
S
L
S
G
Rat
Rattus norvegicus
Q9WVE9
1217
137136
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512436
1711
193720
A212
D
V
A
S
V
P
P
A
A
E
W
A
V
P
Q
Chicken
Gallus gallus
XP_419989
1695
192801
S223
G
S
S
S
S
N
S
S
S
S
A
S
L
A
G
Frog
Xenopus laevis
O42287
1270
143652
D26
V
E
E
R
A
K
H
D
Q
Q
F
H
G
L
K
Zebra Danio
Brachydanio rerio
NP_001138272
1665
190748
S213
N
S
P
K
T
S
S
S
D
W
A
V
P
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
94.5
N.A.
90.6
34.1
N.A.
59.8
83.2
34.1
58
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.4
N.A.
97.2
N.A.
94.5
47.2
N.A.
73.7
92.2
48.5
73.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
0
N.A.
6.6
60
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
0
N.A.
40
86.6
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
12
0
0
12
12
0
67
12
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% D
% Glu:
0
12
12
0
0
0
0
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% F
% Gly:
12
45
0
0
0
0
0
0
0
0
0
0
12
0
56
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
12
% K
% Leu:
45
0
0
0
0
0
0
0
0
0
0
0
56
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
12
12
0
0
0
0
0
12
12
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
12
0
0
0
12
12
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
23
56
67
56
56
23
67
56
12
0
56
0
45
12
% S
% Thr:
0
0
0
0
12
0
45
0
0
45
0
0
0
0
0
% T
% Val:
12
12
0
0
12
0
0
0
0
0
0
12
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
12
12
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _