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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ITSN2 All Species: 19.09
Human Site: S221 Identified Species: 52.5
UniProt: Q9NZM3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZM3 NP_006268.2 1697 193461 S221 L G S S S S T S S T A S L S G
Chimpanzee Pan troglodytes XP_515329 1656 188783 S220 L G S S S S T S S T A S L S G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849291 1695 193027 S221 L G S S S S T S S T A S L S G
Cat Felis silvestris
Mouse Mus musculus Q9Z0R6 1659 188889 S222 L G S S S S T S S T A S L S G
Rat Rattus norvegicus Q9WVE9 1217 137136
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512436 1711 193720 A212 D V A S V P P A A E W A V P Q
Chicken Gallus gallus XP_419989 1695 192801 S223 G S S S S N S S S S A S L A G
Frog Xenopus laevis O42287 1270 143652 D26 V E E R A K H D Q Q F H G L K
Zebra Danio Brachydanio rerio NP_001138272 1665 190748 S213 N S P K T S S S D W A V P Q S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 N.A. 94.5 N.A. 90.6 34.1 N.A. 59.8 83.2 34.1 58 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 97.4 N.A. 97.2 N.A. 94.5 47.2 N.A. 73.7 92.2 48.5 73.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 0 N.A. 6.6 60 0 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 0 N.A. 40 86.6 13.3 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 12 0 12 0 0 12 12 0 67 12 0 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 12 12 0 0 0 0 0 0 % D
% Glu: 0 12 12 0 0 0 0 0 0 12 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % F
% Gly: 12 45 0 0 0 0 0 0 0 0 0 0 12 0 56 % G
% His: 0 0 0 0 0 0 12 0 0 0 0 12 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 12 0 0 0 0 0 0 0 0 12 % K
% Leu: 45 0 0 0 0 0 0 0 0 0 0 0 56 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 12 0 0 12 12 0 0 0 0 0 12 12 0 % P
% Gln: 0 0 0 0 0 0 0 0 12 12 0 0 0 12 12 % Q
% Arg: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 23 56 67 56 56 23 67 56 12 0 56 0 45 12 % S
% Thr: 0 0 0 0 12 0 45 0 0 45 0 0 0 0 0 % T
% Val: 12 12 0 0 12 0 0 0 0 0 0 12 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 12 12 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _