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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKD2L2
All Species:
12.42
Human Site:
T180
Identified Species:
30.37
UniProt:
Q9NZM6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZM6
NP_055201.2
624
73774
T180
N
T
E
W
R
Y
S
T
S
N
T
N
S
P
W
Chimpanzee
Pan troglodytes
XP_001170169
624
73617
T180
N
T
E
W
R
Y
S
T
S
N
T
N
S
P
W
Rhesus Macaque
Macaca mulatta
XP_001112415
607
71728
T180
N
T
E
W
R
Y
S
T
S
N
T
N
S
P
W
Dog
Lupus familis
XP_531915
609
71758
A180
E
T
E
W
K
Y
A
A
P
T
S
S
S
P
W
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLG4
621
73666
P180
N
P
E
W
T
H
T
P
S
S
R
T
A
P
W
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509851
916
103775
A300
G
P
E
W
K
Y
S
A
S
V
S
L
S
P
F
Chicken
Gallus gallus
XP_414617
587
67805
S188
E
P
E
W
K
Y
V
S
A
S
S
F
S
P
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002310
904
103250
E307
T
A
W
R
F
K
D
E
S
S
L
G
E
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1S7
716
80416
K221
A
F
I
Y
A
T
A
K
E
L
E
N
L
K
T
Sea Urchin
Strong. purpuratus
NP_999827
907
103454
E307
T
A
W
V
Y
S
T
E
E
D
L
D
G
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.5
84.7
N.A.
81.4
N.A.
N.A.
45.6
52.4
N.A.
34.8
N.A.
N.A.
N.A.
30.5
33.6
Protein Similarity:
100
99.5
95.8
90.5
N.A.
92.3
N.A.
N.A.
55
69.7
N.A.
50
N.A.
N.A.
N.A.
48.8
49.3
P-Site Identity:
100
100
100
46.6
N.A.
40
N.A.
N.A.
46.6
40
N.A.
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
N.A.
N.A.
66.6
73.3
N.A.
13.3
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
10
0
20
20
10
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
10
0
10
0
0
0
% D
% Glu:
20
0
70
0
0
0
0
20
20
0
10
0
10
0
0
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
10
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
30
10
0
10
0
0
0
0
0
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
20
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
40
0
0
0
0
0
0
0
0
30
0
40
0
0
0
% N
% Pro:
0
30
0
0
0
0
0
10
10
0
0
0
0
70
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
30
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
40
10
60
30
30
10
60
20
10
% S
% Thr:
20
40
0
0
10
10
20
30
0
10
30
10
0
0
10
% T
% Val:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
20
70
0
0
0
0
0
0
0
0
0
0
60
% W
% Tyr:
0
0
0
10
10
60
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _