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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKD2L2
All Species:
9.09
Human Site:
T539
Identified Species:
22.22
UniProt:
Q9NZM6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZM6
NP_055201.2
624
73774
T539
Q
K
D
E
D
K
K
T
K
G
S
G
D
L
A
Chimpanzee
Pan troglodytes
XP_001170169
624
73617
T539
Q
K
D
E
D
K
K
T
K
G
S
G
D
L
A
Rhesus Macaque
Macaca mulatta
XP_001112415
607
71728
T539
R
K
D
E
D
K
K
T
K
G
S
G
D
L
A
Dog
Lupus familis
XP_531915
609
71758
I537
K
P
E
Q
D
E
D
I
S
M
K
G
D
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLG4
621
73666
K538
A
Q
A
K
E
E
K
K
M
Q
T
T
D
L
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509851
916
103775
L665
P
E
L
Q
D
K
D
L
K
E
M
E
D
L
A
Chicken
Gallus gallus
XP_414617
587
67805
F522
E
L
H
I
A
D
L
F
R
Q
S
Y
N
K
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002310
904
103250
G684
E
L
R
Q
D
L
R
G
K
G
H
S
D
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1S7
716
80416
E613
S
M
T
E
H
V
P
E
K
V
A
E
D
I
A
Sea Urchin
Strong. purpuratus
NP_999827
907
103454
C688
E
W
R
Q
E
L
K
C
R
G
H
A
D
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.5
84.7
N.A.
81.4
N.A.
N.A.
45.6
52.4
N.A.
34.8
N.A.
N.A.
N.A.
30.5
33.6
Protein Similarity:
100
99.5
95.8
90.5
N.A.
92.3
N.A.
N.A.
55
69.7
N.A.
50
N.A.
N.A.
N.A.
48.8
49.3
P-Site Identity:
100
100
93.3
33.3
N.A.
26.6
N.A.
N.A.
40
13.3
N.A.
26.6
N.A.
N.A.
N.A.
26.6
20
P-Site Similarity:
100
100
100
60
N.A.
60
N.A.
N.A.
53.3
33.3
N.A.
46.6
N.A.
N.A.
N.A.
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
10
0
0
0
0
0
10
10
0
20
80
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
30
0
60
10
20
0
0
0
0
0
90
0
10
% D
% Glu:
30
10
10
40
20
20
0
10
0
10
0
20
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
50
0
40
0
0
0
% G
% His:
0
0
10
0
10
0
0
0
0
0
20
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
0
0
0
10
0
% I
% Lys:
10
30
0
10
0
40
50
10
60
0
10
0
0
10
0
% K
% Leu:
0
20
10
0
0
20
10
10
0
0
0
0
0
60
0
% L
% Met:
0
10
0
0
0
0
0
0
10
10
10
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
10
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
20
10
0
40
0
0
0
0
0
20
0
0
0
0
0
% Q
% Arg:
10
0
20
0
0
0
10
0
20
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
10
0
40
10
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
30
0
0
10
10
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _