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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKD2L2
All Species:
5.76
Human Site:
Y576
Identified Species:
14.07
UniProt:
Q9NZM6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZM6
NP_055201.2
624
73774
Y576
K
E
R
L
E
K
K
Y
Y
S
M
E
I
Q
D
Chimpanzee
Pan troglodytes
XP_001170169
624
73617
Y576
K
E
R
L
E
K
K
Y
Y
S
M
E
I
Q
D
Rhesus Macaque
Macaca mulatta
XP_001112415
607
71728
Q560
G
F
D
E
N
E
I
Q
K
A
E
Q
M
K
K
Dog
Lupus familis
XP_531915
609
71758
E561
E
N
E
I
Q
S
A
E
Q
M
K
K
W
K
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLG4
621
73666
M564
E
I
Q
E
A
E
Q
M
K
R
W
K
E
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509851
916
103775
E706
Q
Q
K
Y
Y
S
P
E
E
P
A
A
F
L
D
Chicken
Gallus gallus
XP_414617
587
67805
T540
L
K
L
R
K
P
E
T
D
L
G
D
E
N
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002310
904
103250
H759
D
D
D
E
D
S
G
H
S
S
R
R
R
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U1S7
716
80416
V654
V
D
Q
M
Q
E
S
V
F
S
I
V
D
R
I
Sea Urchin
Strong. purpuratus
NP_999827
907
103454
L810
V
S
K
I
D
A
V
L
V
K
L
E
A
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
94.5
84.7
N.A.
81.4
N.A.
N.A.
45.6
52.4
N.A.
34.8
N.A.
N.A.
N.A.
30.5
33.6
Protein Similarity:
100
99.5
95.8
90.5
N.A.
92.3
N.A.
N.A.
55
69.7
N.A.
50
N.A.
N.A.
N.A.
48.8
49.3
P-Site Identity:
100
100
0
6.6
N.A.
0
N.A.
N.A.
6.6
0
N.A.
6.6
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
33.3
40
N.A.
40
N.A.
N.A.
26.6
26.6
N.A.
26.6
N.A.
N.A.
N.A.
60
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
0
0
10
10
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
20
20
0
20
0
0
0
10
0
0
10
10
0
40
% D
% Glu:
20
20
10
30
20
30
10
20
10
0
10
30
20
0
10
% E
% Phe:
0
10
0
0
0
0
0
0
10
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
20
0
0
10
0
0
0
10
0
20
0
10
% I
% Lys:
20
10
20
0
10
20
20
0
20
10
10
20
0
20
10
% K
% Leu:
10
0
10
20
0
0
0
10
0
10
10
0
0
10
20
% L
% Met:
0
0
0
10
0
0
0
10
0
10
20
0
10
10
0
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% P
% Gln:
10
10
20
0
20
0
10
10
10
0
0
10
0
20
0
% Q
% Arg:
0
0
20
10
0
0
0
0
0
10
10
10
10
20
0
% R
% Ser:
0
10
0
0
0
30
10
0
10
40
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
20
0
0
0
0
0
10
10
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% W
% Tyr:
0
0
0
10
10
0
0
20
20
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _