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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKD2L2 All Species: 5.76
Human Site: Y577 Identified Species: 14.07
UniProt: Q9NZM6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NZM6 NP_055201.2 624 73774 Y577 E R L E K K Y Y S M E I Q D D
Chimpanzee Pan troglodytes XP_001170169 624 73617 Y577 E R L E K K Y Y S M E I Q D D
Rhesus Macaque Macaca mulatta XP_001112415 607 71728 K561 F D E N E I Q K A E Q M K K W
Dog Lupus familis XP_531915 609 71758 Q562 N E I Q S A E Q M K K W K D R
Cat Felis silvestris
Mouse Mus musculus Q9JLG4 621 73666 K565 I Q E A E Q M K R W K E R L E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509851 916 103775 E707 Q K Y Y S P E E P A A F L D H
Chicken Gallus gallus XP_414617 587 67805 D541 K L R K P E T D L G D E N L E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001002310 904 103250 S760 D D E D S G H S S R R R G S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U1S7 716 80416 F655 D Q M Q E S V F S I V D R I E
Sea Urchin Strong. purpuratus NP_999827 907 103454 V811 S K I D A V L V K L E A M E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 94.5 84.7 N.A. 81.4 N.A. N.A. 45.6 52.4 N.A. 34.8 N.A. N.A. N.A. 30.5 33.6
Protein Similarity: 100 99.5 95.8 90.5 N.A. 92.3 N.A. N.A. 55 69.7 N.A. 50 N.A. N.A. N.A. 48.8 49.3
P-Site Identity: 100 100 0 6.6 N.A. 0 N.A. N.A. 6.6 0 N.A. 6.6 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 33.3 33.3 N.A. 40 N.A. N.A. 20 33.3 N.A. 26.6 N.A. N.A. N.A. 66.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 10 0 0 10 10 10 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 20 20 0 20 0 0 0 10 0 0 10 10 0 40 20 % D
% Glu: 20 10 30 20 30 10 20 10 0 10 30 20 0 10 30 % E
% Phe: 10 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 10 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % H
% Ile: 10 0 20 0 0 10 0 0 0 10 0 20 0 10 0 % I
% Lys: 10 20 0 10 20 20 0 20 10 10 20 0 20 10 0 % K
% Leu: 0 10 20 0 0 0 10 0 10 10 0 0 10 20 0 % L
% Met: 0 0 10 0 0 0 10 0 10 20 0 10 10 0 0 % M
% Asn: 10 0 0 10 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 10 10 0 0 10 0 0 0 0 0 0 % P
% Gln: 10 20 0 20 0 10 10 10 0 0 10 0 20 0 0 % Q
% Arg: 0 20 10 0 0 0 0 0 10 10 10 10 20 0 20 % R
% Ser: 10 0 0 0 30 10 0 10 40 0 0 0 0 10 10 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 10 10 10 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 10 % W
% Tyr: 0 0 10 10 0 0 20 20 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _