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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EHD2
All Species:
18.18
Human Site:
S451
Identified Species:
57.14
UniProt:
Q9NZN4
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZN4
NP_055416.2
543
61161
S451
W
V
V
T
K
D
K
S
K
Y
D
E
I
F
Y
Chimpanzee
Pan troglodytes
XP_001169755
543
61129
S451
W
V
V
T
K
D
K
S
K
Y
D
E
I
F
Y
Rhesus Macaque
Macaca mulatta
XP_001118235
704
78829
P616
W
V
V
G
K
D
K
P
T
Y
D
E
I
F
Y
Dog
Lupus familis
XP_541532
543
61185
S451
W
V
V
T
K
D
K
S
K
Y
D
E
I
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH64
543
61156
S451
W
V
V
T
K
D
K
S
K
Y
D
E
I
F
Y
Rat
Rattus norvegicus
Q4V8H8
543
61219
S451
W
V
V
T
K
D
K
S
K
Y
D
E
I
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90577
471
54129
A384
F
I
F
K
S
I
L
A
K
T
N
V
S
K
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956357
543
61398
P451
W
V
V
T
K
D
K
P
K
Y
D
E
I
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
56.8
99.2
N.A.
96.6
97
N.A.
N.A.
28.7
N.A.
79.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
65.4
99.8
N.A.
98.7
98.7
N.A.
N.A.
46
N.A.
87.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
80
100
N.A.
100
100
N.A.
N.A.
6.6
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
100
N.A.
N.A.
40
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
88
0
0
0
0
88
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
88
0
0
0
% E
% Phe:
13
0
13
0
0
0
0
0
0
0
0
0
0
88
13
% F
% Gly:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
0
0
0
13
0
0
0
0
0
0
88
0
0
% I
% Lys:
0
0
0
13
88
0
88
0
88
0
0
0
0
13
0
% K
% Leu:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
13
0
0
63
0
0
0
0
13
0
0
% S
% Thr:
0
0
0
75
0
0
0
0
13
13
0
0
0
0
0
% T
% Val:
0
88
88
0
0
0
0
0
0
0
0
13
0
0
0
% V
% Trp:
88
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
88
0
0
0
0
88
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _