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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CD274
All Species:
14.85
Human Site:
S279
Identified Species:
36.3
UniProt:
Q9NZQ7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZQ7
NP_054862.1
290
33275
S279
C
G
I
Q
D
T
N
S
K
K
Q
S
D
T
H
Chimpanzee
Pan troglodytes
XP_001140705
290
33204
S279
C
G
I
Q
D
T
N
S
K
K
Q
S
D
T
H
Rhesus Macaque
Macaca mulatta
NP_001077358
290
33287
S279
S
G
I
R
V
T
N
S
K
K
Q
R
D
T
Q
Dog
Lupus familis
XP_541302
241
27384
H231
V
I
P
E
V
S
H
H
S
S
R
S
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9EP73
290
32762
S279
C
G
V
E
D
T
S
S
K
N
R
N
D
T
Q
Rat
Rattus norvegicus
Q7TPB4
316
34056
S305
A
L
R
P
L
K
H
S
E
N
K
E
D
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506048
345
38605
T329
F
R
P
K
H
S
G
T
A
R
R
R
G
G
G
Chicken
Gallus gallus
XP_424811
315
35995
F302
H
D
C
R
G
P
S
F
E
D
A
E
L
K
Y
Frog
Xenopus laevis
Q68EV1
308
34001
E282
A
G
N
E
E
H
E
E
N
G
E
L
K
T
A
Zebra Danio
Brachydanio rerio
NP_001074091
300
32705
K280
M
R
A
E
E
E
A
K
E
L
E
E
A
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
92
66.2
N.A.
69.6
27.2
N.A.
42.3
36.8
25.3
25.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
94.4
73.7
N.A.
81.3
44.6
N.A.
55.6
54.9
46
45.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
66.6
6.6
N.A.
53.3
13.3
N.A.
0
0
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
33.3
N.A.
86.6
33.3
N.A.
33.3
26.6
33.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
10
0
0
0
10
0
10
0
10
0
10
10
10
% A
% Cys:
30
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
30
0
0
0
0
10
0
0
50
10
0
% D
% Glu:
0
0
0
40
20
10
10
10
30
0
20
30
0
0
0
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
50
0
0
10
0
10
0
0
10
0
0
10
10
30
% G
% His:
10
0
0
0
10
10
20
10
0
0
0
0
0
0
20
% H
% Ile:
0
10
30
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
10
0
10
40
30
10
0
10
10
0
% K
% Leu:
0
10
0
0
10
0
0
0
0
10
0
10
20
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
30
0
10
20
0
10
0
0
0
% N
% Pro:
0
0
20
10
0
10
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
20
0
0
0
0
0
0
30
0
0
0
20
% Q
% Arg:
0
20
10
20
0
0
0
0
0
10
30
20
0
10
0
% R
% Ser:
10
0
0
0
0
20
20
50
10
10
0
30
0
0
0
% S
% Thr:
0
0
0
0
0
40
0
10
0
0
0
0
0
50
0
% T
% Val:
10
0
10
0
20
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _