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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPM5
All Species:
19.09
Human Site:
S340
Identified Species:
46.67
UniProt:
Q9NZQ8
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NZQ8
NP_055370.1
1165
131451
S340
A
L
V
K
A
C
K
S
H
S
Q
E
P
Q
D
Chimpanzee
Pan troglodytes
XP_521720
1064
120176
D300
E
F
V
R
L
F
V
D
N
G
A
D
V
A
D
Rhesus Macaque
Macaca mulatta
XP_001093334
1165
131044
S340
A
L
V
K
A
C
K
S
H
S
Q
E
P
Q
D
Dog
Lupus familis
XP_540789
1174
132628
S351
A
L
V
K
A
C
K
S
H
S
Q
E
A
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJH7
1158
130825
S343
A
L
V
K
A
C
K
S
H
S
Q
E
A
Q
D
Rat
Rattus norvegicus
Q9ESQ5
1208
135322
S388
A
L
V
K
A
C
G
S
S
E
A
S
A
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513927
1579
182519
N431
A
L
L
K
A
S
R
N
H
D
H
F
G
H
E
Chicken
Gallus gallus
XP_422646
1509
172772
N453
A
L
F
K
A
S
R
N
Q
D
H
F
G
R
E
Frog
Xenopus laevis
NP_001155066
1139
131628
C364
A
I
K
S
K
I
P
C
V
V
V
E
G
S
G
Zebra Danio
Brachydanio rerio
NP_001121711
1160
131872
S326
A
L
V
K
A
C
K
S
Q
S
Q
E
A
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.6
95.1
82.1
N.A.
84.4
43
N.A.
22.2
26.6
22.3
57.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
90.3
97
88.7
N.A.
89.9
58.5
N.A.
38.1
41.8
40.5
72.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
93.3
46.6
N.A.
33.3
26.6
13.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
93.3
N.A.
93.3
46.6
N.A.
60
53.3
20
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
90
0
0
0
80
0
0
0
0
0
20
0
40
10
0
% A
% Cys:
0
0
0
0
0
60
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
20
0
10
0
0
60
% D
% Glu:
10
0
0
0
0
0
0
0
0
10
0
60
0
0
20
% E
% Phe:
0
10
10
0
0
10
0
0
0
0
0
20
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
0
30
0
10
% G
% His:
0
0
0
0
0
0
0
0
50
0
20
0
0
10
0
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
80
10
0
50
0
0
0
0
0
0
0
0
% K
% Leu:
0
80
10
0
10
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
20
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
20
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
20
0
50
0
0
50
0
% Q
% Arg:
0
0
0
10
0
0
20
0
0
0
0
0
0
10
0
% R
% Ser:
0
0
0
10
0
20
0
60
10
50
0
10
0
10
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
70
0
0
0
10
0
10
10
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _